PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 471557
Common NameARALYDRAFT_471557, WRKY4
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 511aa    MW: 55533.2 Da    PI: 8.2967
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
471557genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY108.92.4e-34225281259
             --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
    WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
             dDgynWrKYGqK+vkgsefprsYY+Ct +gCpvkkkvers  d++v+ei+Y+g+Hnhe
  471557 225 DDGYNWRKYGQKQVKGSEFPRSYYKCTNPGCPVKKKVERSL-DGQVTEIIYKGQHNHE 281
             8****************************************.***************8 PP
2WRKY105.92.1e-33404462159
             ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
    WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
             ldDgy+WrKYGqK+vkg+++prsYY+Ct+agC v+k+ver+a+dpk+v++tYeg+Hnh+
  471557 404 LDDGYRWRKYGQKVVKGNPYPRSYYKCTTAGCGVRKHVERAATDPKAVVTTYEGKHNHD 462
             59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.803.6E-30219283IPR003657WRKY domain
SuperFamilySSF1182902.62E-26223283IPR003657WRKY domain
SMARTSM007746.6E-39224282IPR003657WRKY domain
PROSITE profilePS5081124.857225283IPR003657WRKY domain
PfamPF031062.1E-26225281IPR003657WRKY domain
Gene3DG3DSA:2.20.25.802.0E-36389464IPR003657WRKY domain
SuperFamilySSF1182901.96E-29396464IPR003657WRKY domain
PROSITE profilePS5081138.17399464IPR003657WRKY domain
SMARTSM007749.5E-39404463IPR003657WRKY domain
PfamPF031065.6E-26405462IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:1900150Biological Processregulation of defense response to fungus
GO:1900425Biological Processnegative regulation of defense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 511 aa     Download sequence    Send to blast
MSEKEEAPST SKSAGAPSRP TLSLPPRPFS EMFFNGGVGF SPGPMTLVSN MFPDSDEFRS  60
FSQLLAGAMT SPATATAATA SDYQRISEGT NSSSGDVDPR FKQNRPTGLM ISQSQSPSMF  120
TVPPGLSPAM LMDSPSFLGL FSPVQGAYGM THQQALAQVT AQAVQANANM QPQTEYPPSS  180
QVQSFSSGQA QIPTSAPLPA QRETSDVTII EHRSQQPLNV DKPADDGYNW RKYGQKQVKG  240
SEFPRSYYKC TNPGCPVKKK VERSLDGQVT EIIYKGQHNH EPPQNTKRGN KDNTANLNGS  300
SVNNNRGSSE LGVSQFQTNS SNKTKREQHE AASQATTTEH LSEASDSEEV GNGETDVREK  360
DENEPDPKRR STEVRVSEPA PAASHRTVTE PRIIVQTTSE VDLLDDGYRW RKYGQKVVKG  420
NPYPRSYYKC TTAGCGVRKH VERAATDPKA VVTTYEGKHN HDLPAAKSSS HAAAAAQLRS  480
DNRPGGLANL NQQQQQQPVA RLRLKEEQTT *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A4e-45225465878Probable WRKY transcription factor 4
2lex_A4e-45225465878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap471557
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4258350.0AF425835.1 Arabidopsis thaliana WRKY transcription factor 4 (WRKY4) mRNA, complete cds.
GenBankAY0456760.0AY045676.1 Arabidopsis thaliana At1g13960/F7A19_5 mRNA, complete cds.
GenBankBT0026290.0BT002629.1 Arabidopsis thaliana At1g13960/F7A19_5 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002890032.10.0probable WRKY transcription factor 4
SwissprotQ9XI900.0WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLD7KBF40.0D7KBF4_ARALL; WRKY DNA-binding protein 4
STRINGfgenesh2_kg.1__1511__AT1G13960.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM15342792
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.10.0WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]