PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis

Family

Dof

Protein Properties

Length: 143aa MW: 15867 Da PI: 8.6863

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
462928006	genome	Tef	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	111.2	4.8e-35	56	112	2	57
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPv.Gggrrk 57 +e+ lkcprC+st+tkfCyynnyslsqPryfCk+CrryWtkGG+lrnvP G ++r 462928006 56 HEQPLKCPRCESTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGSLRNVPWyGEASRA 112 7899*********************************************62555665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	3.0E-25	54	104	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	6.9E-30	58	110	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	25.956	60	114	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	62	98	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 143 aa Download sequence Send to blast
MHICMDSDWL KGIVVPEEAA GMGGSSSPST EQLIACPRQM TMHHPAAADR RLRPQHEQPL 60 KCPRCESTHT KFCYYNNYSL SQPRYFCKTC RRYWTKGGSL RNVPWYGEAS RAPESAISSL 120 GALGLWSGMI GSAHQHHGSS AAI

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	462928006

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT035326	1e-83	BT035326.1 Zea mays full-length cDNA clone ZM_BFb0055G17 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004953626.1	1e-54	dof zinc finger protein 1
Swissprot	Q9FM03	4e-35	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	K3YUL6	3e-53	K3YUL6_SETIT; Uncharacterized protein
STRING	Si017962m	4e-54	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP4704	32	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	2e-37	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]