PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis

Family

MIKC_MADS

Protein Properties

Length: 295aa MW: 33490.2 Da PI: 9.3543

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
462900835	genome	Tef	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	76.3	2.3e-24	41	78	1	38
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEE CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevavi 38 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i 462900835 41 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALI 78 79***********************************9 PP
2	K-box	102.3	6.5e-34	108	204	5	100
K-box 5 sgks.leeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100 s++ ++e +a+++qqe+akL++ i++Lq+++R l+G+ ++++sl++L+qLe +Le++++kiR++Knell+++++++qk+e el+++n +Lr+k++e 462900835 108 SNTGtVAEVNAQYYQQESAKLRQTISSLQNSNRTLVGDAINTMSLRDLKQLEGRLERGINKIRARKNELLYAEVDYMQKREMELHSDNLYLRTKVAE 204 33335999**************************************************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	3.0E-28	33	95	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	26.31	33	78	IPR002100	Transcription factor, MADS-box
CDD	cd00265	3.20E-34	34	104	No hit	No description
PRINTS	PR00404	8.0E-23	35	55	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	3.66E-23	35	102	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.3E-20	42	78	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	8.0E-23	55	70	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	8.0E-23	70	91	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	3.1E-25	117	202	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	14.361	118	208	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 295 aa Download sequence Send to blast
MLNMMADLSC GPSKVKEQPT PANSGPSAGS DKPARGKIEI KRIENTTNRQ VTFCKRRNGL 60 LKKAYELSVL CDAEVALIGS QLLNSVHTLY LFVKATIERY KKANTDTSNT GTVAEVNAQY 120 YQQESAKLRQ TISSLQNSNR TLVGDAINTM SLRDLKQLEG RLERGINKIR ARKNELLYAE 180 VDYMQKREME LHSDNLYLRT KVAENERGHE QPMGMQMEAA STSEYEHMVP YDSRNFLQVS 240 IMQQPQNYSH HLQPTTLQLG SNQKAPKYMC ARNFYHLSVL SQLLVLLGVR ELDNI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1n6j_A	2e-14	34	99	1	63	Myocyte-specific enhancer factor 2B
1n6j_B	2e-14	34	99	1	63	Myocyte-specific enhancer factor 2B
1tqe_P	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
1tqe_Q	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
1tqe_R	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
1tqe_S	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_A	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_B	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_C	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_D	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_E	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
6c9l_F	2e-14	34	99	2	64	Myocyte-specific enhancer factor 2B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the development of floral organs. Acts as C-class protein in association with MADS58. Involved in the control of lodicule number (whorl 2), stamen specification (whorl 3) and floral meristem determinacy (whorl 4), but not in the regulation of carpel morphogenesis. Plays a more predominant role in controlling lodicule development and in specifying stamen identity than MADS58. {ECO:0000269\|PubMed:11828031, ECO:0000269\|PubMed:16326928, ECO:0000269\|PubMed:9869408}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	462900835

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025816639.1	1e-147	MADS-box transcription factor 3 isoform X2
Swissprot	Q40704	1e-124	MADS3_ORYSJ; MADS-box transcription factor 3
TrEMBL	A0A0A8XZ73	1e-156	A0A0A8XZ73_ARUDO; Uncharacterized protein
STRING	Pavir.Ea00226.1.p	1e-142	(Panicum virgatum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP649	37	144

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18960.1	6e-93	MIKC_MADS family protein

Publications ? help Back to Top
Kyozuka J,Shimamoto K Ectopic expression of OsMADS3, a rice ortholog of AGAMOUS, caused a homeotic transformation of lodicules to stamens in transgenic rice plants. Plant Cell Physiol., 2002. 43(1): p. 130-5 [PMID:11828031] Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764]