PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462884744
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family WRKY
Protein Properties Length: 265aa    MW: 29299 Da    PI: 9.8692
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462884744genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY92.33.5e-29106165159
                ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                ++Dgy+WrKYGqK+ +++++pr+Y+rC++a +Cpvkkkv+rsaed+++++  YegeHnh 
  462884744 106 VKDGYQWRKYGQKVTRDNPYPRAYFRCAYApSCPVKKKVQRSAEDKSMLVAQYEGEHNHA 165
                58***************************99****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.0E-28101166IPR003657WRKY domain
PROSITE profilePS5081126.085101164IPR003657WRKY domain
SuperFamilySSF1182904.05E-25102165IPR003657WRKY domain
SMARTSM007746.7E-34106166IPR003657WRKY domain
PfamPF031063.2E-24107164IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009620Biological Processresponse to fungus
GO:0009751Biological Processresponse to salicylic acid
GO:0010200Biological Processresponse to chitin
GO:1900425Biological Processnegative regulation of defense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 265 aa     Download sequence    Send to blast
MRRNVLAKSS RVLLFWDRAL LAATFVRVTH TSAARGSCRS SARPCREPQG EAEADERGEP  60
AADQRAGRHP RRRPCPPASP RHVARRPRVR TVHARAEPAD AEANLVKDGY QWRKYGQKVT  120
RDNPYPRAYF RCAYAPSCPV KKKVQRSAED KSMLVAQYEG EHNHAQCAQS ELVSDASTSQ  180
QGPSSGSLPC SISINSLGRT ITLGLTNQGS GFNDNAVVGE VAAPEFRNVL VDEMVTLLKN  240
DSEFMESLTS AVTARMMEKI SDRIF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A7e-211011641274Probable WRKY transcription factor 4
2lex_A7e-211011641274Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Regulates negatively basal innate immunity and XA21-mediated defense against X.oryzae pv. oryzae (Xoo) (By similarity). {ECO:0000250|UniProtKB:Q6EPZ0, ECO:0000250|UniProtKB:Q6QHD1}.
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Regulates negatively basal innate immunity and XA21-mediated defense against X.oryzae pv. oryzae (Xoo) (PubMed:19825552, PubMed:21961049). {ECO:0000250|UniProtKB:Q6QHD1, ECO:0000269|PubMed:19825552, ECO:0000269|PubMed:21961049}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462884744
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Might be activated by XA21 in the nucleus upon pathogen infection (PubMed:19825552). Induced by biotic elicitors (e.g. fungal chitin oligosaccharide) (PubMed:23462973). Induced by pathogen infection (e.g. M.grisea and X.oryzae pv. oryzae (Xoo)) (PubMed:16528562, PubMed:24093634). Accumulates after treatment with benzothiadiazole (BTH) and salicylic acid (SA) (PubMed:17601827, PubMed:16528562, PubMed:24093634). Transactivated by WRKY45 (PubMed:24093634). {ECO:0000269|PubMed:16528562, ECO:0000269|PubMed:17601827, ECO:0000269|PubMed:23462973, ECO:0000269|PubMed:24093634, ECO:0000303|PubMed:19825552}.
UniProtINDUCTION: Might be activated by XA21 in the nucleus upon pathogen infection (PubMed:20118235). Induced by biotic elicitors (e.g. fungal chitin oligosaccharide) (By similarity). Induced by pathogen infection (e.g. M.grisea and X.oryzae pv. oryzae (Xoo)). Accumulates after treatment with benzothiadiazole (BTH) and salicylic acid (SA) (PubMed:16528562). Transactivated by WRKY45 (By similarity). {ECO:0000250|UniProtKB:Q6EPZ0, ECO:0000269|PubMed:16528562, ECO:0000303|PubMed:20118235}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004956832.14e-93WRKY transcription factor WRKY62
SwissprotB8BF915e-70WRK62_ORYSI; WRKY transcription factor WRKY62
SwissprotQ6EPZ05e-70WRK62_ORYSJ; WRKY transcription factor WRKY62
TrEMBLK3ZW131e-91K3ZW13_SETIT; Uncharacterized protein
STRINGSi030794m2e-92(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP129212834
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G31800.12e-43WRKY DNA-binding protein 18
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang Y,Wang L
    The WRKY transcription factor superfamily: its origin in eukaryotes and expansion in plants.
    BMC Evol. Biol., 2005. 5: p. 1
    [PMID:15629062]
  3. Wu KL,Guo ZJ,Wang HH,Li J
    The WRKY family of transcription factors in rice and Arabidopsis and their origins.
    DNA Res., 2005. 12(1): p. 9-26
    [PMID:16106749]
  4. Chen X, et al.
    A conserved threonine residue in the juxtamembrane domain of the XA21 pattern recognition receptor is critical for kinase autophosphorylation and XA21-mediated immunity.
    J. Biol. Chem., 2010. 285(14): p. 10454-63
    [PMID:20118235]
  5. Peng Y,Bartley LE,Canlas P,Ronald PC
    OsWRKY IIa Transcription Factors Modulate Rice Innate Immunity.
    Rice (N Y), 2010. 3(1): p. 36-42
    [PMID:21961049]
  6. Park CJ,Ronald PC
    Cleavage and nuclear localization of the rice XA21 immune receptor.
    Nat Commun, 2012. 3: p. 920
    [PMID:22735448]
  7. Chujo T, et al.
    OsWRKY28, a PAMP-responsive transrepressor, negatively regulates innate immune responses in rice against rice blast fungus.
    Plant Mol. Biol., 2013. 82(1-2): p. 23-37
    [PMID:23462973]
  8. Nakayama A, et al.
    Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice.
    BMC Plant Biol., 2013. 13: p. 150
    [PMID:24093634]
  9. Hou Y, et al.
    JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators.
    BMC Plant Biol., 2015. 15: p. 286
    [PMID:26646110]
  10. Liu J, et al.
    Alternative Splicing of Rice WRKY62 and WRKY76 Transcription Factor Genes in Pathogen Defense.
    Plant Physiol., 2016. 171(2): p. 1427-42
    [PMID:27208272]