PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462875379
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family C2H2
Protein Properties Length: 356aa    MW: 39457.2 Da    PI: 7.9097
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462875379genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.30.000255072323
               ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
               C+  +Cgk+F + s L++H  +H
  462875379 50 CSyeNCGKTFVDVSALRKHAHVH 72
               77779**************9887 PP
2zf-C2H220.11.7e-0677101123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                y C+  +Cgk F ++s LkrH  tH
  462875379  77 YICQepNCGKKFVDSSKLKRHYLTH 101
                889999****************999 PP
3zf-C2H220.71.1e-06107131123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                + Cp  dCgk Fs   nL++H++tH
  462875379 107 FICPhpDCGKAFSLDFNLRSHLKTH 131
                78**********************9 PP
4zf-C2H212.50.00045137161123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                + Cp   Cgk F++   Lk H + H
  462875379 137 HICPfpACGKKFTSDFKLKAHVKAH 161
                6799999***************998 PP
5zf-C2H217.31.4e-05198223123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                y+Cp   C+k + +++ L+ H++t H
  462875379 198 YVCPyeGCDKAYIHSYKLNLHLKTmH 223
                99*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.2E-134372IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0134872IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.3854877IPR007087Zinc finger, C2H2
PROSITE patternPS0002805072IPR007087Zinc finger, C2H2
SuperFamilySSF576676.54E-951101No hitNo description
Gene3DG3DSA:3.30.160.602.0E-137397IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.001577101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015714.23377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.11E-1288140No hitNo description
Gene3DG3DSA:3.30.160.604.3E-1898132IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0019107131IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.196107136IPR007087Zinc finger, C2H2
PROSITE patternPS000280109131IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.8E-8135161IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.021137161IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.93137166IPR007087Zinc finger, C2H2
PROSITE patternPS000280139161IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.6E-10194223IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.03E-6194222No hitNo description
SMARTSM003550.0031198223IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.099198228IPR007087Zinc finger, C2H2
PROSITE patternPS000280200223IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 356 aa     Download sequence    Send to blast
MALEFICASD WRQSQAQNSS DGHKSSKENP KVLEAEAPKP EPTSEILFLC SYENCGKTFV  60
DVSALRKHAH VHGERQYICQ EPNCGKKFVD SSKLKRHYLT HTGQKDFICP HPDCGKAFSL  120
DFNLRSHLKT HALENYHICP FPACGKKFTS DFKLKAHVKA HEKTGTPVAV QHTPPPEKPQ  180
STMKSSTPAP ASYADRPYVC PYEGCDKAYI HSYKLNLHLK TMHPDHGQEE NGKHTAPSGQ  240
HAVNEPTYQY NYAEIGDPAP NPKRSKPSSS HKVSSSKVYN VKVSSAMPAD ITGVKNQWSG  300
KATYEDDSEE TEEDPGNNLE GSLELRRDTN IARLVVSGSK RTVALQLCSV LPGEAV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-34501638119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462875379
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001136556.10.0uncharacterized protein LOC100216676
SwissprotQ2V3L32e-85YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A3L6EAM61e-180A0A3L6EAM6_MAIZE; Putative zinc finger protein
TrEMBLA0A3L6RD381e-180A0A3L6RD38_PANMI; Putative zinc finger protein
TrEMBLB4FJ721e-180B4FJ72_MAIZE; C2H2 transcription factor
STRINGGRMZM2G175000_P010.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.29e-88C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]