PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462854956
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family C2H2
Protein Properties Length: 432aa    MW: 48622.6 Da    PI: 9.079
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462854956genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2110.0013166188323
                ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                C+   Cgk F +   L++H  +H
  462854956 166 CSyeGCGKIFIDAGALRKHAHVH 188
                77779**************9887 PP
2zf-C2H214.88.4e-05193217123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                y C+  +Cgk F ++s LkrH   H
  462854956 193 YICHyeNCGKKFLDSSKLKRHFLIH 217
                89*******************8877 PP
3zf-C2H218.84.3e-06244269123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                ++C+   Cg++F++ s L+ Hir  H
  462854956 244 HVCQypECGRRFTQESKLRAHIRAqH 269
                689999*****************888 PP
4zf-C2H216.13.1e-05306331123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                y+Cp   C+k + + + L+ H+r+ H
  462854956 306 YVCPygGCDKAYIHEYKLNLHLRKeH 331
                9***********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.607.1E-13160190IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.388164193IPR007087Zinc finger, C2H2
SMARTSM003550.0079164188IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.02E-6165189No hitNo description
PROSITE patternPS000280166188IPR007087Zinc finger, C2H2
SuperFamilySSF576672.35E-9189223No hitNo description
Gene3DG3DSA:3.30.160.609.6E-14191219IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015714.066193222IPR007087Zinc finger, C2H2
SMARTSM003550.013193217IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280195217IPR007087Zinc finger, C2H2
SuperFamilySSF576672.95E-10224270No hitNo description
Gene3DG3DSA:3.30.160.607.3E-12230267IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.697244273IPR007087Zinc finger, C2H2
SMARTSM003550.0047244269IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280246269IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.7E-9298329IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576678.15E-6301329No hitNo description
SMARTSM003550.0016306331IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.39306336IPR007087Zinc finger, C2H2
PROSITE patternPS000280308331IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 432 aa     Download sequence    Send to blast
AQPLWEKRRE KRKVTLARLR LHPTPSGGTW TRGVNGIHCH ISSRRQTGRS PPSHQTRAPT  60
SWLSYPPHPC LRPFPSPDSQ SLTLLACSSP PPPPAGSLAS EMQAPARRRH RWVKEWVPQD  120
MVIAGGPCAL YKWVREDRLA SLKAKDKDQG AESAKPEPNT EVLFLCSYEG CGKIFIDAGA  180
LRKHAHVHGE RQYICHYENC GKKFLDSSKL KRHFLIHTGE KNFAFSLDFN LKAHMKTHSA  240
DNYHVCQYPE CGRRFTQESK LRAHIRAQHE KNPGASTMNH NPPEHHHPKP VKSSATPPAP  300
TAERPYVCPY GGCDKAYIHE YKLNLHLRKE HPNHDQDAGA QVAASSKGSM SKNSHRSKPN  360
IAAKMPPPRI PKHKGGYTTP SPAINVPGEH QWPGKVLYQD DSEETEEEGD NVEDGWRYRA  420
ASSDDEETED EE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-261662658114PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462854956
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021316183.10.0zinc finger transcription factor YY1 isoform X2
SwissprotQ2V3L31e-101YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A3L6EPA80.0A0A3L6EPA8_MAIZE; Putative zinc finger protein
STRINGSb04g022470.11e-180(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-97C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]