PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

HD-ZIP

Protein Properties

Length: 232aa MW: 26609.8 Da PI: 6.2626

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
332898	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.9	2e-19	75	128	4	57
-SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHHC CS Homeobox 4 RttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakekk 57 ++++t+eq++ Le F +++++ ++e++A +lgL+ rqV vWFqNrRa++k+ 332898 75 KRKLTDEQVHMLEYSFGNEHKLESGRKEKIAGELGLDPRQVAVWFQNRRARWKN 128 4589************************************************95 PP
2	HD-ZIP_I/II	119.9	1.4e-38	74	165	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 +kr+l++eqv++LE sF +e+kLe+ rK+++a eLgl+prqvavWFqnrRAR+k+k+lE++y++Lk+++d+++ +++Le++ +L+e+l+e 332898 74 RKRKLTDEQVHMLEYSFGNEHKLESGRKEKIAGELGLDPRQVAVWFQNRRARWKNKKLEEEYAKLKNHHDTVVLGQCQLESQILKLKEQLSE 165 8****************************************************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00389	7.5E-18	72	133	IPR001356	Homeobox domain
PROSITE profile	PS50071	15.92	74	129	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.13E-17	74	131	IPR009057	Homeodomain-like
CDD	cd00086	1.32E-15	74	130	No hit	No description
Pfam	PF00046	1.1E-16	75	128	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.3E-20	76	136	IPR009057	Homeodomain-like
PRINTS	PR00031	2.4E-5	100	109	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	104	127	IPR017970	Homeobox, conserved site
PRINTS	PR00031	2.4E-5	109	125	IPR000047	Helix-turn-helix motif

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009733	Biological Process	response to auxin
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 232 aa Download sequence Send to blast
MDHGRLMDDQ MMLGSQVYPY TTQTQNSHCI IVNQIDGSSS GEGSKPVKRR RKRRSKGSSA 60 TNEEDVAEIG GMLRKRKLTD EQVHMLEYSF GNEHKLESGR KEKIAGELGL DPRQVAVWFQ 120 NRRARWKNKK LEEEYAKLKN HHDTVVLGQC QLESQILKLK EQLSEAQSEI RKLSERLEEM 180 PTNSSSSSLS VEANDAPTDF ELAPETNYTI PFYMLDNNYL QSMEYWDGLY V*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	47	53	KRRRKRR
2	72	77	LRKRKL

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may play a regulatory role in auxin/cytokinin signaling during root development. {ECO:0000269\|PubMed:15567172}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00591	DAP	Transfer from AT5G66700	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	332898

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA), by salt stress, by indole-3-acetic acid (IAA) and during darkness conditions. Down-regulated by cytokinin. {ECO:0000269\|PubMed:15567172, ECO:0000269\|PubMed:16055682}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY683477	0.0	AY683477.1 Arabidopsis thaliana homeodomain protein (HB53) mRNA, complete cds.
GenBank	BT024847	0.0	BT024847.1 Arabidopsis thaliana At5g66700 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002866745.1	1e-174	homeobox-leucine zipper protein ATHB-53
Swissprot	Q9LVR0	1e-144	ATB53_ARATH; Homeobox-leucine zipper protein ATHB-53
TrEMBL	D7MME0	1e-172	D7MME0_ARALL; Uncharacterized protein
STRING	fgenesh1_pm.C_scaffold_8002241	1e-173	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM12602	17	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66700.1	1e-144	homeobox 53

Link Out ? help Back to Top
Phytozome	332898
Entrez Gene	9302817

Publications ? help Back to Top
González-Grandío E, et al. Abscisic acid signaling is controlled by a BRANCHED1/HD-ZIP I cascade in Arabidopsis axillary buds. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(2): p. E245-E254 [PMID:28028241]