PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

MYB

Protein Properties

Length: 325aa MW: 36404 Da PI: 7.7194

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
331925	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	61.2	2.2e-19	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg WT+eEd +l+ +++q+G+++W++I++ g+ R++k+c++rw +yl 331925 14 RGQWTPEEDNKLASYIAQHGTRNWRLIPKNAGLQRCGKSCRLRWTNYL 61 89********************************************97 PP
2	Myb_DNA-binding	44.6	3.3e-14	68	110	2	46
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 g +++ E+ ++v+ + lG++ W++Ia ++ gRt++++k++w++ 331925 68 GQFSETEEHIIVKFHSVLGNR-WSLIAGQLP-GRTDNDVKNYWNT 110 789****************.*****.*********97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.6E-25	5	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	26.472	9	65	IPR017930	Myb domain
SuperFamily	SSF46689	3.56E-29	11	108	IPR009057	Homeodomain-like
SMART	SM00717	3.2E-14	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	5.3E-18	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	1.58E-11	17	61	No hit	No description
Gene3D	G3DSA:1.10.10.60	4.0E-23	65	116	IPR009057	Homeodomain-like
SMART	SM00717	3.0E-11	66	114	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	19.614	66	116	IPR017930	Myb domain
Pfam	PF00249	1.9E-12	68	110	IPR001005	SANT/Myb domain
CDD	cd00167	1.40E-7	70	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010090	Biological Process	trichome morphogenesis
GO:0048658	Biological Process	anther wall tapetum development
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MGRIPCCEKE NVKRGQWTPE EDNKLASYIA QHGTRNWRLI PKNAGLQRCG KSCRLRWTNY 60 LRPDLKHGQF SETEEHIIVK FHSVLGNRWS LIAGQLPGRT DNDVKNYWNT KLKKKLSGMG 120 IDPVTHKPFS HLMAEITTTL NPPQVSHLAE AALGCFKDEM LHLLTKKRVD LNQINFSNHN 180 PNANPNNFNQ IADNEAGKIK MSGLDHGNGI MKLWDMGNGF SYGSSSSSFG NEERNDGSAS 240 PAVAAWRGHG GIRTAVAETA AAEEEERRKL KGEVVDQEEI GSEGGRGDGM MMMMRNHHQQ 300 QQHVFNVDNV LWDLQADDLI NHMV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	2e-28	14	116	7	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the DNA sequence 5'-CCAACC-3'. Regulates directly PME5, UND and GLOX1 (PubMed:21673079). Essential for tapetum development in anthers and microsporogenesis (PubMed:12848824, PubMed:21673079). Regulates the timing of tapetal programmed cell death (PCD) which is critical for pollen development. May act through the activation of UND, encoding an A1 aspartic protease (PubMed:21673079). Required for anther development by regulating tapetum development, callose dissolution and exine formation. Acts upstream of A6 and FAR2/MS2, two genes required for pollen exine formation (PubMed:17727613). Negatively regulates trichome endoreduplication and trichome branching (PubMed:12848824). {ECO:0000269\|PubMed:12848824, ECO:0000269\|PubMed:17727613, ECO:0000269\|PubMed:21673079}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00564	DAP	Transfer from AT5G56110	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	331925

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY519639	0.0	AY519639.1 Arabidopsis thaliana MYB transcription factor (At5g56110) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002864434.1	0.0	transcription factor MYB80
Swissprot	Q9XHV0	0.0	MYB80_ARATH; Transcription factor MYB80
TrEMBL	D7ML80	0.0	D7ML80_ARALL; AtMYB103/AtMYB80
STRING	fgenesh1_pm.C_scaffold_8001268	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10005	26	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G56110.1	1e-175	myb domain protein 103

Link Out ? help Back to Top
Phytozome	331925
Entrez Gene	9300510

Publications ? help Back to Top
Li SF,Iacuone S,Parish RW Suppression and restoration of male fertility using a transcription factor. Plant Biotechnol. J., 2007. 5(2): p. 297-312 [PMID:17309685] Qian H, et al. Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis. Ecotoxicology, 2015. 24(1): p. 163-71 [PMID:25348600] Xiong SX, et al. The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana. Plant J., 2016. 88(6): p. 936-946 [PMID:27460657] Verma N,Burma PK Regulation of tapetum-specific A9 promoter by transcription factors AtMYB80, AtMYB1 and AtMYB4 in Arabidopsis thaliana and Nicotiana tabacum. Plant J., 2017. 92(3): p. 481-494 [PMID:28849604] Li DD,Xue JS,Zhu J,Yang ZN Gene Regulatory Network for Tapetum Development in Arabidopsis thaliana. Front Plant Sci, 2017. 8: p. 1559 [PMID:28955355]