PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 316aa MW: 35146.7 Da PI: 6.5215

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
327641	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	46.4	7.3e-15	113	164	1	55
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r++h ++Er+RR+++N+ + Lr+l+P++ + ++ + a+i+ A+++Ik+L+ 327641 113 QRMTHIAVERNRRQQMNEHLTSLRSLMPPS---YIQRGDQASIVGGAIDFIKELE 164 79**************************...9****************996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	3.5E-14	111	168	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.97E-14	111	168	No hit	No description
SuperFamily	SSF47459	4.71E-17	112	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.126	112	163	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.2E-12	113	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.4E-11	118	169	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 316 aa Download sequence Send to blast
MGGLMRFGEL GEQFGQISET TIEEKIPFLQ MLQCIEHPYT TTEPNQFLQS LLRIQTLESN 60 SCLTLETTIK RDPGQTDDPE KDPRTETGAA TVKEKRKRKR TRAPKNKDEV EKQRMTHIAV 120 ERNRRQQMNE HLTSLRSLMP PSYIQRGDQA SIVGGAIDFI KELEQLLQSL EAEKRNDGTN 180 ETPKTASCSS SSSRACTNSS VSSVSTTSED GFTARFGGGE TAEVEATVIQ NHVSLKVRCK 240 RGKGQILKAI VSIEELKLGI LHLTISSSFD FVIYSFNLKI EDGCKLGSAD EIATTVHQIF 300 EQINGEVMWS NLSRT*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	113	124	RMTHIAVERNRR

Cis-element ? help Back to Top
Source	Link
PlantRegMap	327641

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by heat treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY099780	0.0	AY099780.1 Arabidopsis thaliana putative bHLH DNA-binding protein (At4g01460) mRNA, complete cds.
GenBank	AY128881	0.0	AY128881.1 Arabidopsis thaliana putative bHLH DNA-binding protein (At4g01460) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002874978.1	0.0	transcription factor bHLH57
Swissprot	Q9M128	0.0	BH057_ARATH; Transcription factor bHLH57
TrEMBL	D7M4V3	0.0	D7M4V3_ARALL; Basic helix-loop-helix family protein
STRING	fgenesh1_pm.C_scaffold_6002861	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14696	17	21

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G01460.1	1e-173	bHLH family protein

Link Out ? help Back to Top
Phytozome	327641
Entrez Gene	9308961

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]