PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus

Family

MYB

Protein Properties

Length: 584aa MW: 64349.2 Da PI: 7.9158

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
29846.m000184	genome	JCVI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	50.5	4.6e-16	76	122	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT eEde l +av+ + g++Wk+Ia+ ++ R++ qc +rwqk+l 29846.m000184 76 KGGWTLEEDETLRNAVAAFKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 122 688***************************.**********986 PP
2	Myb_DNA-binding	59.6	6.8e-19	128	174	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd+++ ++v+++G+ W+ Ia+ ++ gR +kqc++rw+++l 29846.m000184 128 KGPWTQEEDDKITELVAKYGPTKWSVIAKSLP-GRIGKQCRERWHNHL 174 79****************************.***********97 PP
3	Myb_DNA-binding	54.6	2.4e-17	180	223	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE+ l +a++ +G++ W+ Ia+ ++ gRt++++k++w++ 29846.m000184 180 KDAWTLEEEMALMNAHRIHGNK-WAEIAKVLP-GRTDNSIKNHWNS 223 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	14.816	71	122	IPR017930	Myb domain
SMART	SM00717	8.1E-14	75	124	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-14	76	122	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	5.46E-15	77	132	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.0E-18	78	132	IPR009057	Homeodomain-like
CDD	cd00167	3.19E-12	79	122	No hit	No description
PROSITE profile	PS51294	31.539	123	178	IPR017930	Myb domain
SuperFamily	SSF46689	1.32E-31	125	221	IPR009057	Homeodomain-like
SMART	SM00717	6.3E-18	127	176	IPR001005	SANT/Myb domain
Pfam	PF00249	4.3E-18	128	174	IPR001005	SANT/Myb domain
CDD	cd00167	9.04E-16	130	174	No hit	No description
Gene3D	G3DSA:1.10.10.60	8.1E-28	133	181	IPR009057	Homeodomain-like
PROSITE profile	PS51294	22.065	179	229	IPR017930	Myb domain
SMART	SM00717	1.4E-16	179	227	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-15	180	223	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.4E-23	182	229	IPR009057	Homeodomain-like
CDD	cd00167	7.98E-13	182	225	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 584 aa Download sequence Send to blast
MSSTAIPATS LQEEEEEMDE AKIEECCLEN KQLTAASSSS LSEGSGSATL KSPGVSSPAT 60 ASPTHRRTTG PIRRAKGGWT LEEDETLRNA VAAFKGKSWK KIAEFFPDRS EVQCLHRWQK 120 VLNPDLVKGP WTQEEDDKIT ELVAKYGPTK WSVIAKSLPG RIGKQCRERW HNHLNPDIKK 180 DAWTLEEEMA LMNAHRIHGN KWAEIAKVLP GRTDNSIKNH WNSSLKKKLD FYLATGKLPP 240 VAKSDIVFSS RKLPSVAKNG SQDGIKDINN KHSVFKMYKE SDSTAQTSSG TTDVCKLEED 300 SKNQLESSLL VRDLATSSSF LPNESADSEG VECKPNSFTA DLSCCNSEPL RKCESCGINN 360 EIGEGKFIGS QLHFGTSSYG SLYYEPPQLG ICTPIHVDPL IVHHVQHEYC SSPIASPISF 420 FTPPCVKNSD LSSQSPESIL RIAAKSFPNT PSIFRKRKVG SQVHMLQSKS SKVSQEPVEG 480 RLQVSNGQGR TEYTSEKTES QDGSLSHSPC RDNSTIRPND KAFNASPPYR LKSKRTAVFK 540 SVERQLEFTF DRDRCDSAKS VGLSANGSSI VTEDCSHAAK MGIT

Sequence ? help Back to Top

Protein Sequence Length: 584 aa Download sequence Send to blast

MSSTAIPATS LQEEEEEMDE AKIEECCLEN KQLTAASSSS LSEGSGSATL KSPGVSSPAT  60
ASPTHRRTTG PIRRAKGGWT LEEDETLRNA VAAFKGKSWK KIAEFFPDRS EVQCLHRWQK  120
VLNPDLVKGP WTQEEDDKIT ELVAKYGPTK WSVIAKSLPG RIGKQCRERW HNHLNPDIKK  180
DAWTLEEEMA LMNAHRIHGN KWAEIAKVLP GRTDNSIKNH WNSSLKKKLD FYLATGKLPP  240
VAKSDIVFSS RKLPSVAKNG SQDGIKDINN KHSVFKMYKE SDSTAQTSSG TTDVCKLEED  300
SKNQLESSLL VRDLATSSSF LPNESADSEG VECKPNSFTA DLSCCNSEPL RKCESCGINN  360
EIGEGKFIGS QLHFGTSSYG SLYYEPPQLG ICTPIHVDPL IVHHVQHEYC SSPIASPISF  420
FTPPCVKNSD LSSQSPESIL RIAAKSFPNT PSIFRKRKVG SQVHMLQSKS SKVSQEPVEG  480
RLQVSNGQGR TEYTSEKTES QDGSLSHSPC RDNSTIRPND KAFNASPPYR LKSKRTAVFK  540
SVERQLEFTF DRDRCDSAKS VGLSANGSSI VTEDCSHAAK MGIT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	1e-68	75	229	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	1e-68	75	229	5	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	29846.m000184

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ567344	0.0	AJ567344.1 Populus tremula x Populus tremuloides mRNA for MYB transcription factor R3 type (myb gene).

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002532327.1	0.0	transcription factor MYB3R-3 isoform X1
Swissprot	Q6R032	1e-175	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	B9T258	0.0	B9T258_RICCO; Myb3r3, putative
STRING	XP_002532327.1	0.0	(Ricinus communis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6616	34	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-165	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	29846.m000184
Entrez Gene	8268281

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]