PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus

Family

C2H2

Protein Properties

Length: 631aa MW: 69354.8 Da PI: 8.7744

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
29647.m001996	genome	JCVI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.8	1.9e-05	114	136	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H 29647.m001996 114 FVCEICNKGFQRDQNLQLHRRGH 136 89*******************88 PP
2	zf-C2H2	15.2	6e-05	190	212	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ 29647.m001996 190 WKCDKCSKKYAVQSDWKAHQKTC 212 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	2.2E-5	113	136	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.1E-8	113	136	No hit	No description
SMART	SM00355	0.017	114	136	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	114	136	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	116	136	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	155	185	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	7.7E-5	178	211	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.1E-8	185	211	No hit	No description
SMART	SM00355	94	190	210	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 631 aa Download sequence Send to blast
MSNITGGEGS FSSGNTGEEV QQLQEKQQQL QNHFHGSNLS GPNSGATNSN GSTSQQTAVK 60 KKRNLPGTPG NNNKTLETNE KGVLDCSKRY EFSRDPNADV IALSPTTLMA TNRFVCEICN 120 KGFQRDQNLQ LHRRGHNLPW KLRQRTTTEV KKRVYICPEP TCVHHNPARA LGDLTGIKKH 180 FSRKHGEKKW KCDKCSKKYA VQSDWKAHQK TCGTREYKCD CGTIFSRIYV PALVCNLALL 240 SISLLTLLFN DQSCRRDSFI THRAFCDALA EENNKVNQGL TGSHLQNQMP ELMSSMPLTT 300 NTNTSIGISD FNSFDPKNPL KSLPQELVPM PFKSMNMAGG MFSSSSGTLF GGPRSIASTS 360 SSLQLSSNSS SGYNYLQDGK NGCQISSSAQ MSATALLQKA AQMGATASNS INSPMMQKSF 420 ASSMACPDQI IPIRPQLPRP PSFGGVQQHN NTTSYDHFPS SQLLDQTHLV GINGGGYNQP 480 NGTLQKGQQE MSQFFDPTSS SGMSDMGMLS TMFMGTDQNP GFMKNIEHSN NDHQDSGNTT 540 SLIHGRAHSM ERTASGPSRL VGHNGESSDM MTRDFMGIGG SRPANLHEQQ QQQQQRMEMG 600 AMSQQRMPMM SHFQQQLSLG ESAMEKPIWE V

Sequence ? help Back to Top

Protein Sequence Length: 631 aa Download sequence Send to blast

MSNITGGEGS FSSGNTGEEV QQLQEKQQQL QNHFHGSNLS GPNSGATNSN GSTSQQTAVK  60
KKRNLPGTPG NNNKTLETNE KGVLDCSKRY EFSRDPNADV IALSPTTLMA TNRFVCEICN  120
KGFQRDQNLQ LHRRGHNLPW KLRQRTTTEV KKRVYICPEP TCVHHNPARA LGDLTGIKKH  180
FSRKHGEKKW KCDKCSKKYA VQSDWKAHQK TCGTREYKCD CGTIFSRIYV PALVCNLALL  240
SISLLTLLFN DQSCRRDSFI THRAFCDALA EENNKVNQGL TGSHLQNQMP ELMSSMPLTT  300
NTNTSIGISD FNSFDPKNPL KSLPQELVPM PFKSMNMAGG MFSSSSGTLF GGPRSIASTS  360
SSLQLSSNSS SGYNYLQDGK NGCQISSSAQ MSATALLQKA AQMGATASNS INSPMMQKSF  420
ASSMACPDQI IPIRPQLPRP PSFGGVQQHN NTTSYDHFPS SQLLDQTHLV GINGGGYNQP  480
NGTLQKGQQE MSQFFDPTSS SGMSDMGMLS TMFMGTDQNP GFMKNIEHSN NDHQDSGNTT  540
SLIHGRAHSM ERTASGPSRL VGHNGESSDM MTRDFMGIGG SRPANLHEQQ QQQQQRMEMG  600
AMSQQRMPMM SHFQQQLSLG ESAMEKPIWE V

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-28	186	277	3	66	Zinc finger protein JACKDAW
5b3h_F	4e-28	186	277	3	66	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	29647.m001996

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015575643.1	0.0	protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-101	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	B9S3T6	0.0	B9S3T6_RICCO; Nucleic acid binding protein, putative
STRING	XP_002520655.1	0.0	(Ricinus communis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	3e-89	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	29647.m001996

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]