PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Oryza sativa f. spontanea
GRF Family
Species TF ID Description
ONIVA02G30970.1GRF family protein
ONIVA02G31920.1GRF family protein
ONIVA02G36590.1GRF family protein
ONIVA03G30460.1GRF family protein
ONIVA03G34380.1GRF family protein
ONIVA04G21020.1GRF family protein
ONIVA04G23220.1GRF family protein
ONIVA06G01450.1GRF family protein
ONIVA06G01450.2GRF family protein
ONIVA06G01450.3GRF family protein
ONIVA06G07790.1GRF family protein
ONIVA07G11690.1GRF family protein
ONIVA11G16660.1GRF family protein
ONIVA11G16660.3GRF family protein
ONIVA12G12410.1GRF family protein
GRF Family Introduction

Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Kim JH, Choi D, Kende H.
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J. 2003 Oct;36(1):94-104.
PMID: 12974814