PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Cucurbita pepo subsp. pepo
GRF Family
Species TF ID Description
XP_023512137.1GRF family protein
XP_023516139.1GRF family protein
XP_023516140.1GRF family protein
XP_023517130.1GRF family protein
XP_023525289.1GRF family protein
XP_023525291.1GRF family protein
XP_023526497.1GRF family protein
XP_023526499.1GRF family protein
XP_023528302.1GRF family protein
XP_023529192.1GRF family protein
XP_023529974.1GRF family protein
XP_023529975.1GRF family protein
XP_023532788.1GRF family protein
XP_023536990.1GRF family protein
XP_023537378.1GRF family protein
XP_023537379.1GRF family protein
XP_023537380.1GRF family protein
XP_023537381.1GRF family protein
XP_023539890.1GRF family protein
XP_023543094.1GRF family protein
XP_023546920.1GRF family protein
XP_023546921.1GRF family protein
XP_023546922.1GRF family protein
XP_023546923.1GRF family protein
XP_023547102.1GRF family protein
GRF Family Introduction

Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Kim JH, Choi D, Kende H.
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J. 2003 Oct;36(1):94-104.
PMID: 12974814