PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Physcomitrella patens
BES1 Family
Species TF ID Description
Pp3c12_13650V3.1.pBES1 family protein
Pp3c12_13650V3.2.pBES1 family protein
Pp3c12_13650V3.3.pBES1 family protein
Pp3c20_1120V3.1.pBES1 family protein
Pp3c20_1120V3.2.pBES1 family protein
Pp3c20_1120V3.3.pBES1 family protein
Pp3c20_1120V3.4.pBES1 family protein
Pp3c23_21930V3.1.pBES1 family protein
Pp3c23_21930V3.2.pBES1 family protein
Pp3c4_6860V3.1.pBES1 family protein
Pp3c4_6860V3.2.pBES1 family protein
Pp3c4_6860V3.3.pBES1 family protein
Pp3c4_6860V3.4.pBES1 family protein
Pp3c4_6860V3.5.pBES1 family protein
Pp3c5_4880V3.1.pBES1 family protein
Pp3c5_4880V3.3.pBES1 family protein
Pp3c6_22390V3.1.pBES1 family protein
Pp3c6_22390V3.2.pBES1 family protein
Pp3c6_22390V3.3.pBES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330