PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Malus domestica
ARF Family
Species TF ID Description
MDP0000123466ARF family protein
MDP0000131481ARF family protein
MDP0000134824ARF family protein
MDP0000138853ARF family protein
MDP0000138860ARF family protein
MDP0000139073ARF family protein
MDP0000143749ARF family protein
MDP0000153538ARF family protein
MDP0000173151ARF family protein
MDP0000179650ARF family protein
MDP0000185253ARF family protein
MDP0000194603ARF family protein
MDP0000211459ARF family protein
MDP0000214352ARF family protein
MDP0000221322ARF family protein
MDP0000225980ARF family protein
MDP0000232116ARF family protein
MDP0000232417ARF family protein
MDP0000256621ARF family protein
MDP0000258032ARF family protein
MDP0000259062ARF family protein
MDP0000268306ARF family protein
MDP0000294251ARF family protein
MDP0000310875ARF family protein
MDP0000319957ARF family protein
MDP0000412781ARF family protein
MDP0000750392ARF family protein
MDP0000876321ARF family protein
MDP0000886637ARF family protein
MDP0000929655ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969