PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Lactuca sativa
MYB Family
Species TF ID Description
Lsa000264MYB family protein
Lsa000624MYB family protein
Lsa000705MYB family protein
Lsa000774MYB family protein
Lsa001002MYB family protein
Lsa001266MYB family protein
Lsa001572MYB family protein
Lsa002875MYB family protein
Lsa003301MYB family protein
Lsa003349MYB family protein
Lsa003506MYB family protein
Lsa003943MYB family protein
Lsa005096MYB family protein
Lsa005217MYB family protein
Lsa005262MYB family protein
Lsa005644MYB family protein
Lsa005721MYB family protein
Lsa005989MYB family protein
Lsa006019MYB family protein
Lsa006136MYB family protein
Lsa006227MYB family protein
Lsa006232MYB family protein
Lsa007048MYB family protein
Lsa007401MYB family protein
Lsa007623MYB family protein
Lsa007751MYB family protein
Lsa008127MYB family protein
Lsa008822MYB family protein
Lsa009092MYB family protein
Lsa009134MYB family protein
Lsa009210MYB family protein
Lsa009317MYB family protein
Lsa009361MYB family protein
Lsa009424MYB family protein
Lsa009574MYB family protein
Lsa010336MYB family protein
Lsa010815MYB family protein
Lsa011256MYB family protein
Lsa011281MYB family protein
Lsa011539MYB family protein
Lsa012007MYB family protein
Lsa012275MYB family protein
Lsa012288MYB family protein
Lsa012737MYB family protein
Lsa013029MYB family protein
Lsa013049MYB family protein
Lsa013065MYB family protein
Lsa013253MYB family protein
Lsa013283MYB family protein
Lsa013437MYB family protein
Lsa013567MYB family protein
Lsa014003MYB family protein
Lsa014195MYB family protein
Lsa014824MYB family protein
Lsa015221MYB family protein
Lsa015278MYB family protein
Lsa015488MYB family protein
Lsa015504MYB family protein
Lsa015528MYB family protein
Lsa015609MYB family protein
Lsa016279MYB family protein
Lsa016343MYB family protein
Lsa016957MYB family protein
Lsa016967MYB family protein
Lsa016974MYB family protein
Lsa017033MYB family protein
Lsa017360MYB family protein
Lsa017404MYB family protein
Lsa017588MYB family protein
Lsa017717MYB family protein
Lsa018242MYB family protein
Lsa018525MYB family protein
Lsa018538MYB family protein
Lsa018727MYB family protein
Lsa018813MYB family protein
Lsa018822MYB family protein
Lsa019065MYB family protein
Lsa019235MYB family protein
MYB Family Introduction

MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the "oncogene" v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.

In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as "MYB1R factors", with two as "R2R3-type MYB" factors, and with three repeats as "MYB3R" factors.

Stracke R, Werber M, Weisshaar B.
The R2R3-MYB gene family in Arabidopsis thaliana.
Curr Opin Plant Biol. 2001 Oct;4(5):447-56. Review.
PMID: 11597504