PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Camelina sativa
GeBP Family
Species TF ID Description
Csa00441s040.1GeBP family protein
Csa00441s040.2GeBP family protein
Csa01g005680.1GeBP family protein
Csa01g008770.1GeBP family protein
Csa01g044210.1GeBP family protein
Csa02g053450.1GeBP family protein
Csa02g055270.1GeBP family protein
Csa02g055280.1GeBP family protein
Csa03g015150.1GeBP family protein
Csa04g049820.1GeBP family protein
Csa05g017750.1GeBP family protein
Csa06g038950.1GeBP family protein
Csa07g056680.1GeBP family protein
Csa07g062970.1GeBP family protein
Csa08g029690.1GeBP family protein
Csa09g091840.1GeBP family protein
Csa09g096270.1GeBP family protein
Csa10g017770.1GeBP family protein
Csa10g033280.1GeBP family protein
Csa10g049670.1GeBP family protein
Csa10g049680.1GeBP family protein
Csa10g051430.1GeBP family protein
Csa11g019370.1GeBP family protein
Csa11g019380.1GeBP family protein
Csa11g041480.1GeBP family protein
Csa11g059700.1GeBP family protein
Csa11g061430.1GeBP family protein
Csa12g028020.1GeBP family protein
Csa12g062990.1GeBP family protein
Csa12g077450.1GeBP family protein
Csa13g017080.1GeBP family protein
Csa13g037810.1GeBP family protein
Csa14g014260.1GeBP family protein
Csa15g005930.1GeBP family protein
Csa15g009460.1GeBP family protein
Csa16433s010.1GeBP family protein
Csa16g047290.1GeBP family protein
Csa16g053490.1GeBP family protein
Csa17g015580.1GeBP family protein
Csa19g007130.1GeBP family protein
Csa19g011480.1GeBP family protein
Csa19g048010.1GeBP family protein
Csa19g058050.1GeBP family protein
Csa20g057280.1GeBP family protein
GeBP Family Introduction

Understanding the role of transcription factors (TFs) is essential in reconstructing developmental regulatory networks. The plant-specific GeBP TF family of Arabidopsis thaliana (Arabidopsis) comprises 21 members, all of unknown function. A subset of four members, the founding member GeBP and GeBP-like proteins (GPL) 1, 2, and 3, shares a conserved C-terminal domain. Here we report that GeBP/GPL genes represent a newly defined class of leucine-zipper (Leu-zipper) TFs and that they play a redundant role in cytokinin hormone pathway regulation. Specifically, we demonstrate using yeast, in vitro, and split-yellow fluorescent protein in planta assays that GeBP/GPL proteins form homo- and heterodimers through a noncanonical Leu-zipper motif located in the C-terminal domain. A triple loss-of-function mutant of the three most closely related genes gebp gpl1 gpl2 shows a reduced sensitivity to exogenous cytokinins in a subset of cytokinin responses such as senescence and growth, whereas root inhibition is not affected. We find that transcript levels of type-A cytokinin response genes, which are involved in the negative feedback regulation of cytokinin signaling, are higher in the triple mutant. Using a GPL version that acts as a constitutive transcriptional activator, we show that the regulation of Arabidopsis response regulators (ARRs) is mediated by at least one additional, as yet unknown, repressor acting genetically downstream in the GeBP/GPL pathway. Our results indicate that GeBP/GPL genes encode a new class of unconventional Leu-zipper TF proteins and suggest that their role in the cytokinin pathway is to antagonize the negative feedback regulation on ARR genes to trigger the cytokinin response.

Chevalier F, Perazza D, Laporte F, Le Henanff G, Hornitschek P, Bonneville JM, Herzog M, Vachon G
GeBP and GeBP-Like Proteins Are Noncanonical Leucine-Zipper Transcription Factors That Regulate Cytokinin Response in Arabidopsis
Plant Physiol. 2008 Mar;146(3):1142-54.
PMID: 18162594