PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Actinidia chinensis
ZF-HD Family
Species TF ID Description
Achn015051ZF-HD family protein
Achn041581ZF-HD family protein
Achn074571ZF-HD family protein
Achn121961ZF-HD family protein
Achn121971ZF-HD family protein
Achn128581ZF-HD family protein
Achn135381ZF-HD family protein
Achn137771ZF-HD family protein
Achn157391ZF-HD family protein
Achn166931ZF-HD family protein
Achn169621ZF-HD family protein
Achn182951ZF-HD family protein
Achn197641ZF-HD family protein
Achn209741ZF-HD family protein
Achn211081ZF-HD family protein
Achn217631ZF-HD family protein
Achn224031ZF-HD family protein
Achn229151ZF-HD family protein
Achn234371ZF-HD family protein
Achn235261ZF-HD family protein
Achn243291ZF-HD family protein
Achn245021ZF-HD family protein
Achn260831ZF-HD family protein
Achn286491ZF-HD family protein
Achn288711ZF-HD family protein
Achn293421ZF-HD family protein
Achn294741ZF-HD family protein
Achn316681ZF-HD family protein
Achn370131ZF-HD family protein
Achn385871ZF-HD family protein
ZF-HD Family Introduction

This group of sequences described by a 54-residue domain found in the N-terminal region of plant proteins, the vast majority of which contain a ZF-HD class homeobox domain toward the C terminus. The region between the two domains typically is rich in low complexity sequence. The companion ZF-HD homeobox domain is described in INTERPRO:IPR006455.

A one-hybrid screen resulted in the cloning of four different members of a novel class of plant homeodomain proteins, which are most likely involved in the mesophyll-specific expression of the C4 PEPCase gene in C4 species of the genus Flaveria. Inspection of the homeodomains of the four proteins reveals that they share many common features with homeodomains described so far, but there are also significant differences. Interestingly, this class of homeodomain proteins occurs also in Arabidopsis thaliana and other C3 plants. One-hybrid experiments as well as in vitro DNA binding studies confirmed that these novel homeodomain proteins specifically interact with the proximal region of the C4 PEPCase (C4 phosphoenolpyruvate carboxylase) gene. The N-terminal domains of the homeodomain proteins contain highly conserved sequence motifs. Two-hybrid experiments show that these motifs are sufficient to confer homo- or heterodimer formation between the proteins. Mutagenesis of conserved cysteine residues within the dimerization domain indicates that these residues are essential for dimer formation. Therefore, we designate this novel class of homeobox proteins ZF-HD, for zinc finger homeodomain protein. Our data suggest that the ZF-HD class of homeodomain proteins may be involved in the establishment of the characteristic expression pattern of the C4 PEPCase gene.

Windhovel A, Hein I, Dabrowa R, Stockhaus J.
Characterization of a novel class of plant homeodomain proteins that bind to the C4 phosphoenolpyruvate carboxylase gene of Flaveria trinervia.
Plant Mol Biol. 2001 Jan;45(2):201-14.
PMID: 11289511