PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Aethionema arabicum
TCP Family
Species TF ID Description
AA10G00391TCP family protein
AA159G00002TCP family protein
AA15G00099TCP family protein
AA21G00301TCP family protein
AA26G00213TCP family protein
AA26G00528TCP family protein
AA31G00127TCP family protein
AA32G00617TCP family protein
AA38G00109TCP family protein
AA44G00073TCP family protein
AA44G00156TCP family protein
AA53G00904TCP family protein
AA54G00098TCP family protein
AA54G00421TCP family protein
AA55G00056TCP family protein
AA55G00057TCP family protein
AA57G00120TCP family protein
AA5G00182TCP family protein
AA5G00219TCP family protein
AA60G00085TCP family protein
AA96G00032TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426