PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Aethionema arabicum
ARF Family
Species TF ID Description
AA102G00149ARF family protein
AA21G00384ARF family protein
AA27G00186ARF family protein
AA31G00188ARF family protein
AA32G00876ARF family protein
AA39G00205ARF family protein
AA39G00248ARF family protein
AA3G00067ARF family protein
AA43G00006ARF family protein
AA53G00430ARF family protein
AA54G00244ARF family protein
AA54G00428ARF family protein
AA5G00105ARF family protein
AA65G00088ARF family protein
AA8G00331ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969