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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Species | TF ID | Description |
---|---|---|
Glycine soja (33) | KHM99082.1 | NF-YB family protein |
KHN01010.1 | NF-YB family protein | |
KHN02369.1 | NF-YB family protein | |
KHN02981.1 | NF-YB family protein | |
KHN03372.1 | NF-YB family protein | |
KHN03548.1 | NF-YB family protein | |
KHN03685.1 | NF-YB family protein | |
KHN03737.1 | NF-YB family protein | |
KHN09471.1 | NF-YB family protein | |
KHN10436.1 | NF-YB family protein | |
KHN11144.1 | NF-YB family protein | |
KHN15166.1 | NF-YB family protein | |
KHN15471.1 | NF-YB family protein | |
KHN15652.1 | NF-YB family protein | |
KHN16115.1 | NF-YB family protein | |
KHN16948.1 | NF-YB family protein | |
KHN20229.1 | NF-YB family protein | |
KHN20809.1 | NF-YB family protein | |
KHN21151.1 | NF-YB family protein | |
KHN22167.1 | NF-YB family protein | |
KHN26570.1 | NF-YB family protein | |
KHN29106.1 | NF-YB family protein | |
KHN30700.1 | NF-YB family protein | |
KHN31648.1 | NF-YB family protein | |
KHN34093.1 | NF-YB family protein | |
KHN34225.1 | NF-YB family protein | |
KHN38217.1 | NF-YB family protein | |
KHN38630.1 | NF-YB family protein | |
KHN40791.1 | NF-YB family protein | |
KHN42266.1 | NF-YB family protein | |
KHN43896.1 | NF-YB family protein | |
KHN44907.1 | NF-YB family protein | |
KHN46582.1 | NF-YB family protein |
NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).
As with NF-YA, NF-YB and NF-YC families have well-described subunit interaction and DNA-binding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NF-YB and NF-YC have structural and amino acid homology to histone fold motifs. Specifically, NF-YB is related to the histone fold motifs of H2B histones, while NF-YC subunits are related to H2A histones (Mantovani, 1999).
Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982