PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Zmw_sc02021.1.g00040.1

Organism

Zoysia matrella

Taxonomic ID

38722

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia

Family

GRF

Protein Properties

Length: 397aa MW: 42622.6 Da PI: 9.5096

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zmw_sc02021.1.g00040.1	genome	ZGD	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	76.1	3.7e-24	142	186	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+epgrCrRtDGKkWRCs+++ + +k+CErH+hrgr+rsrk++e+ Zmw_sc02021.1.g00040.1.sm.mk 142 DPEPGRCRRTDGKKWRCSKEAAPQSKYCERHMHRGRNRSRKPVET 186 79****************************************997 PP
2	QLQ	55.8	1.4e-19	81	116	2	37
QLQ 2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 +FT+aQ ++L++Q+l+yKyLaa++ vPp+L+++i++ Zmw_sc02021.1.g00040.1.sm.mk 81 PFTPAQYEELEQQALIYKYLAAGVAVPPDLVVPIRR 116 8*********************************86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	4.0E-10	80	116	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	1.6E-13	81	115	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	21.979	81	116	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	24.711	142	186	IPR014977	WRC domain
Pfam	PF08879	2.5E-20	143	185	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 397 aa Download sequence Send to blast
MPYASLSPAG GGDHRSSTAT ASLLPFCRSS PLSSAYATTA PFFALPVVAV LFARSVPWGN 60 GGSGGVGEDA QLSGRWTRPL PFTPAQYEEL EQQALIYKYL AAGVAVPPDL VVPIRRGLDS 120 LATRFYGHPT LSYGSYFGKK LDPEPGRCRR TDGKKWRCSK EAAPQSKYCE RHMHRGRNRS 180 RKPVETQLLP HSQSPSAMAP IAAQPLAAAA SGRNFQSHSL YPAIAGSNGG GRGSNISSPF 240 SSSMGSSQLN LDNTATYAAL GGGTGKALRY TGYGIRSLAD EHNQLISEAL DLSSMENQWR 300 LPSYPQLLRQ STVNSLSKMD RQPLSFLGND FGTVGSVKQE NQLRPFFDEW PKSRDSWPGL 360 GDENTNLTSF SATQLSISTP MASSDFSAAS SQSPNGE

Sequence ? help Back to Top

Protein Sequence Length: 397 aa Download sequence Send to blast

MPYASLSPAG GGDHRSSTAT ASLLPFCRSS PLSSAYATTA PFFALPVVAV LFARSVPWGN  60
GGSGGVGEDA QLSGRWTRPL PFTPAQYEEL EQQALIYKYL AAGVAVPPDL VVPIRRGLDS  120
LATRFYGHPT LSYGSYFGKK LDPEPGRCRR TDGKKWRCSK EAAPQSKYCE RHMHRGRNRS  180
RKPVETQLLP HSQSPSAMAP IAAQPLAAAA SGRNFQSHSL YPAIAGSNGG GRGSNISSPF  240
SSSMGSSQLN LDNTATYAAL GGGTGKALRY TGYGIRSLAD EHNQLISEAL DLSSMENQWR  300
LPSYPQLLRQ STVNSLSKMD RQPLSFLGND FGTVGSVKQE NQLRPFFDEW PKSRDSWPGL  360
GDENTNLTSF SATQLSISTP MASSDFSAAS SQSPNGE

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:24532604). Transcription activator that plays a regulatory role in grain development (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates the expression of genes promoting cell proliferation (PubMed:26187814, PubMed:26936408). Activates the expression of expansin genes to promote cell expansion and grain size (PubMed:27250747). May promote grain size by activating brassinosteroid responses (PubMed:27250747). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable) (PubMed:27250747, PubMed:27250749, PubMed:27107174). {ECO:0000269\|PubMed:24532604, ECO:0000269\|PubMed:26187814, ECO:0000269\|PubMed:26936408, ECO:0000269\|PubMed:27107174, ECO:0000269\|PubMed:27250747, ECO:0000269\|PubMed:27250749, ECO:0000305\|PubMed:26187814, ECO:0000305\|PubMed:27107174, ECO:0000305\|PubMed:27250747, ECO:0000305\|PubMed:27250749}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: The microRNA396c negatively regulates GRF4 at the transcriptional level. {ECO:0000269\|PubMed:26187814, ECO:0000269\|PubMed:26936408, ECO:0000269\|PubMed:27107174, ECO:0000269\|PubMed:27250747}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025791920.1	0.0	growth-regulating factor 4-like
Swissprot	Q6ZIK5	1e-160	GRF4_ORYSJ; Growth-regulating factor 4
TrEMBL	A0A2T7FAX5	0.0	A0A2T7FAX5_9POAL; Uncharacterized protein
STRING	Pavir.Aa00789.1.p	0.0	(Panicum virgatum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2463	34	76

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Kuijt SJ, et al. Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors. Plant Physiol., 2014. 164(4): p. 1952-66 [PMID:24532604] Hu J, et al. A Rare Allele of GS2 Enhances Grain Size and Grain Yield in Rice. Mol Plant, 2015. 8(10): p. 1455-65 [PMID:26187814] Sun P, et al. OsGRF4 controls grain shape, panicle length and seed shattering in rice. J Integr Plant Biol, 2016. 58(10): p. 836-847 [PMID:26936408] Li S, et al. The OsmiR396c-OsGRF4-OsGIF1 regulatory module determines grain size and yield in rice. Plant Biotechnol. J., 2016. 14(11): p. 2134-2146 [PMID:27107174] Che R, et al. Control of grain size and rice yield by GL2-mediated brassinosteroid responses. Nat Plants, 2015. 2: p. 15195 [PMID:27250747] Duan P, et al. Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice. Nat Plants, 2015. 2: p. 15203 [PMID:27250749]