PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zmw_sc01126.1.g00260.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family GRF
Protein Properties Length: 442aa    MW: 47317 Da    PI: 8.3379
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zmw_sc01126.1.g00260.1genomeZGD-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC77.81.1e-24151195145
                           WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                                   d+epgrCrRtDGKkWRCs+++ +++k+CErH+hrgr+rsrk++e+
  Zmw_sc01126.1.g00260.1.sm.mk 151 DPEPGRCRRTDGKKWRCSKEAAPDSKYCERHMHRGRNRSRKPVET 195
                                   79****************************************997 PP

2QLQ57.93e-2065100237
                           QLQ   2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                                   +FT+aQ+++L++Q+l+yKyL+a++ vPp+L+++i++
  Zmw_sc01126.1.g00260.1.sm.mk  65 PFTPAQFEELEQQALIYKYLVAGVAVPPDLVVPIRR 100
                                   8*********************************86 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009516.6E-1164100IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166622.06565100IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088803.7E-146599IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166725.486151195IPR014977WRC domain
PfamPF088794.7E-21152194IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 442 aa     Download sequence    Send to blast
MAMPYASLSP AGGGGGGGDH RSSTTTTTTT ASLLPFCRAS PLSAGSGGGL GEDAQMSGRW  60
ARPLPFTPAQ FEELEQQALI YKYLVAGVAV PPDLVVPIRR GLDSLATRFY GHPTRTVPVL  120
LFYLLLLLLT TPSLPYRFWL AYGSYFGKKL DPEPGRCRRT DGKKWRCSKE AAPDSKYCER  180
HMHRGRNRSR KPVETQLVPQ SQPPSAMAPI AAQPLTAATS GGNFQSHSLY PAIAGSNGGG  240
EGSNISSPFT SSLSSSQLNL DNAATYAALG GGTGKDLRYT GYGIRSLADE HNQLISEAID  300
SSMANQWRLP PSHNSSFPLP SYPQLGALSD LGQSTVNSLS KMDRQPLSFL GNDFGTVGSV  360
KQENQLRPFF DEWPKSRESW PCLGDENANL ASFSATQLSM SIPMASSDFS AATPASSQSP  420
NDLYQTKSPD ACAADMNGIR FP
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:24532604). Transcription activator that plays a regulatory role in grain development (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates the expression of genes promoting cell proliferation (PubMed:26187814, PubMed:26936408). Activates the expression of expansin genes to promote cell expansion and grain size (PubMed:27250747). May promote grain size by activating brassinosteroid responses (PubMed:27250747). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable) (PubMed:27250747, PubMed:27250749, PubMed:27107174). {ECO:0000269|PubMed:24532604, ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747, ECO:0000269|PubMed:27250749, ECO:0000305|PubMed:26187814, ECO:0000305|PubMed:27107174, ECO:0000305|PubMed:27250747, ECO:0000305|PubMed:27250749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: The microRNA396c negatively regulates GRF4 at the transcriptional level. {ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025791920.10.0growth-regulating factor 4-like
SwissprotQ6ZIK51e-180GRF4_ORYSJ; Growth-regulating factor 4
TrEMBLA0A2T7FAX50.0A0A2T7FAX5_9POAL; Uncharacterized protein
STRINGPavir.Aa00789.1.p0.0(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP24633476
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Kuijt SJ, et al.
    Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.
    Plant Physiol., 2014. 164(4): p. 1952-66
    [PMID:24532604]
  3. Hu J, et al.
    A Rare Allele of GS2 Enhances Grain Size and Grain Yield in Rice.
    Mol Plant, 2015. 8(10): p. 1455-65
    [PMID:26187814]
  4. Sun P, et al.
    OsGRF4 controls grain shape, panicle length and seed shattering in rice.
    J Integr Plant Biol, 2016. 58(10): p. 836-847
    [PMID:26936408]
  5. Li S, et al.
    The OsmiR396c-OsGRF4-OsGIF1 regulatory module determines grain size and yield in rice.
    Plant Biotechnol. J., 2016. 14(11): p. 2134-2146
    [PMID:27107174]
  6. Che R, et al.
    Control of grain size and rice yield by GL2-mediated brassinosteroid responses.
    Nat Plants, 2015. 2: p. 15195
    [PMID:27250747]
  7. Duan P, et al.
    Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice.
    Nat Plants, 2015. 2: p. 15203
    [PMID:27250749]