PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zmw_sc00344.1.g00330.1
Organism
Zoysia matrella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family E2F/DP
Protein Properties Length: 390aa    MW: 43104.6 Da    PI: 7.3881
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zmw_sc00344.1.g00330.1genomeZGD-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.59.2e-2349114171
                         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                                     rk+ksL+ll+++f++l+ +++ ++v l+++ak+L    v  +rRRiYDi+NVLe+++++ +++kn++ w g
  Zmw_sc00344.1.g00330.1.sm.mkhc  49 RKQKSLGLLCSNFVALYDREDVEAVGLDDAAKRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYAWLG 114
                                     79****************9999************...**..****************************87 PP
2E2F_TDP71.87.4e-23186252162
                         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliekk 62 
                                     rkeksL+lltq+f+kl+ + e ++++l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek 
  Zmw_sc00344.1.g00330.1.sm.mkhc 186 RKEKSLGLLTQNFVKLFLTMEVETISLDEAARLLLGEghaesNMRTKVRRLYDIANVLSSLNLIEKA 252
                                     79****************************************************************5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.6E-2545115IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.43E-1648113IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.2E-2749114IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.4E-2050114IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.2E-19183252IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.45E-10186252IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.2E-24186260IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.3E-17187252IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 390 aa     Download sequence    Send to blast
MDAAAAAAVA GPSSSSGAGA SAQPQPTVPQ AAVQGAAASK SCRHHAYSRK QKSLGLLCSN  60
FVALYDREDV EAVGLDDAAK RLGVERRRIY DIVNVLESVG ILVRRAKNRY AWLGFGGVPA  120
ALKELKVSFE IPVIFSCHCE VASDDEDDDK LGDADEDDES EKLSQSVDNL SDKPGALPCR  180
LRSDHRKEKS LGLLTQNFVK LFLTMEVETI SLDEAARLLL GEGHAESNMR TKVRRLYDIA  240
NVLSSLNLIE KAFERQLGQG SRSDFVYGPF HPSGAKKQEI GDHLVREERK SIQDWENLAV  300
TFRPQYQNQV MTNGHFYPHV ANRKEHSFLD RSAPIRLDSP TVGSGTRSRC LRLQHQFGHH  360
LTRVIEERAL DMSSTTSRRI LLVEGRAVVS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A6e-36482523222Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002436789.11e-125E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ43e-72E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0D9WNU11e-124A0A0D9WNU1_9ORYZ; Uncharacterized protein
STRINGLPERR06G08240.11e-125(Leersia perrieri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]