PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zosma323g00110.1
Common NameZOSMA_323G00110
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Alismatales; Zosteraceae; Zostera
Family E2F/DP
Protein Properties Length: 453aa    MW: 50064.7 Da    PI: 4.5003
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zosma323g00110.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP856e-27145210171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL+llt+kf++ll+++++g+++ln++a++L   dv  ++RRiYDi+NVLe+++liekk kn+irwkg
  Zosma323g00110.1 145 RYDSSLGLLTKKFINLLKHADDGNLDLNKAATTL---DV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 210
                       6899******************************...**..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-28142211IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.8E-17145208IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.0E-33145210IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.9E-24147210IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.70E-41221326No hitNo description
SuperFamilySSF1440747.85E-31222326No hitNo description
PfamPF164211.4E-29226324IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 453 aa     Download sequence    Send to blast
MSAAGREVPL PMRHGQTPGR ILQRDIPFPT STPSFFNPDD YHCFSSVRTC AAAGTDDTTE  60
MLIVRTPLKT KSVHQDSEIV ESSEWATSSG YAALNNPLMT PVSGKTEKIT SRSKTGKGMR  120
SLPQTPSANI GSPSCNTSTP AGTCRYDSSL GLLTKKFINL LKHADDGNLD LNKAATTLDV  180
QKRRIYDITN VLEGIGLIEK KLKNRIRWKG HNVLRPIDVD EDVAVLQADV ENLNTKEREI  240
DEQISEAKAR LTELTENENN QRWLFVSEED IKGLPCFQNE TLIAIKAPHG TTLEVPDPDE  300
ADYSQRRYRI VVRSTMGSID VYLVSQFEKN FEEMAAIEAP QSLPPAIPDL GEPGEESNEN  360
RTPLEVEGDN NQRIMRIVPS DVDTESDYWL LSDPGVSITD LWKADSEVPW DGMDTEEFPL  420
TSVSTSQPPT QTQRIEGCPG NSNNNNNSNT PS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-23140210173PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017700050.11e-174transcription factor E2FB-like
SwissprotQ9FNY01e-120E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0K9PB170.0A0A0K9PB17_ZOSMR; Transcription factor (E2F)
STRINGXP_010246568.11e-169(Nelumbo nucifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-121E2F transcription factor 1
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]