PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM5G885700_P02
Common NameC2H133, LOC100193305
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family C2H2
Protein Properties Length: 354aa    MW: 40203 Da    PI: 7.7729
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM5G885700_P02genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.60.000416486323
                       ET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                       C+   Cgk+F +   L++H  +H
  GRMZM5G885700_P02 64 CSyeGCGKTFFDAGALRKHAHVH 86
                       77779**************9887 PP

2zf-C2H215.16.6e-0591115123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        y C+  +Cgk F ++s LkrH   H
  GRMZM5G885700_P02  91 YICHyeNCGKKFLDSSKLKRHFLIH 115
                        89*******************8877 PP

3zf-C2H221.84.9e-07121145123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        ++Cp   Cgk Fs   nLk H++tH
  GRMZM5G885700_P02 121 FVCPheGCGKAFSLDFNLKAHMKTH 145
                        89**********************9 PP

4zf-C2H219.23.4e-06151176123
                        EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                        ++C+   Cg++F++ s L+ Hir  H
  GRMZM5G885700_P02 151 HVCQypECGRRFTQESKLRAHIRAqH 176
                        689999*****************888 PP

5zf-C2H215.54.9e-05220245123
                        EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                        y+Cp   C+k + + + L+ H+++ H
  GRMZM5G885700_P02 220 YVCPydGCDKAYIHEYKLNLHLKKeH 245
                        9**********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.6E-135888IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.00326286IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.7626291IPR007087Zinc finger, C2H2
SuperFamilySSF576671.03E-66387No hitNo description
PROSITE patternPS0002806486IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.4E-1489111IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015714.06691120IPR007087Zinc finger, C2H2
SMARTSM003550.01391115IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028093115IPR007087Zinc finger, C2H2
SuperFamilySSF576673.87E-14102154No hitNo description
Gene3DG3DSA:3.30.160.604.2E-20112148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.321121150IPR007087Zinc finger, C2H2
SMARTSM003554.3E-4121145IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280123145IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.8E-8150173IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0047151176IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.24151176IPR007087Zinc finger, C2H2
SuperFamilySSF576675.18E-7153176No hitNo description
PROSITE patternPS000280153176IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.2E-9212242IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.18E-7215242No hitNo description
SMARTSM003550.0024220245IPR015880Zinc finger, C2H2-like
PROSITE profilePS501578.891220250IPR007087Zinc finger, C2H2
PROSITE patternPS000280222245IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0006310anatomytassel floret
PO:0006339anatomyjuvenile vascular leaf
PO:0006340anatomyadult vascular leaf
PO:0006341anatomyprimary shoot system
PO:0006354anatomyear floret
PO:0006505anatomycentral spike of ear inflorescence
PO:0008018anatomytransition vascular leaf
PO:0009001anatomyfruit
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009054anatomyinflorescence bract
PO:0009066anatomyanther
PO:0009074anatomystyle
PO:0009084anatomypericarp
PO:0009089anatomyendosperm
PO:0020040anatomyleaf base
PO:0020104anatomyleaf sheath
PO:0020126anatomytassel inflorescence
PO:0020127anatomyprimary root
PO:0020136anatomyear inflorescence
PO:0020142anatomystem internode
PO:0020148anatomyshoot apical meristem
PO:0025142anatomyleaf tip
PO:0025287anatomyseedling coleoptile
PO:0001007developmental stagepollen development stage
PO:0001009developmental stageD pollen mother cell meiosis stage
PO:0001052developmental stagevascular leaf expansion stage
PO:0001053developmental stagevascular leaf post-expansion stage
PO:0001083developmental stageinflorescence development stage
PO:0001094developmental stageplant embryo coleoptilar stage
PO:0001095developmental stageplant embryo true leaf formation stage
PO:0001180developmental stageplant proembryo stage
PO:0007001developmental stageearly whole plant fruit ripening stage
PO:0007003developmental stageIL.03 full inflorescence length reached stage
PO:0007006developmental stageIL.00 inflorescence just visible stage
PO:0007015developmental stageradicle emergence stage
PO:0007016developmental stagewhole plant flowering stage
PO:0007022developmental stageseed imbibition stage
PO:0007026developmental stageFL.00 first flower(s) open stage
PO:0007031developmental stagemid whole plant fruit ripening stage
PO:0007032developmental stagewhole plant fruit formation stage up to 10%
PO:0007045developmental stagecoleoptile emergence stage
PO:0007063developmental stageLP.07 seven leaves visible stage
PO:0007065developmental stageLP.05 five leaves visible stage
PO:0007072developmental stageLP.18 eighteen leaves visible stage
PO:0007094developmental stageLP.01 one leaf visible stage
PO:0007101developmental stageLP.09 nine leaves visible stage
PO:0007104developmental stageLP.15 fifteen leaves visible stage
PO:0007106developmental stageLP.03 three leaves visible stage
PO:0007112developmental stage1 main shoot growth stage
PO:0007116developmental stageLP.11 eleven leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007633developmental stageendosperm development stage
PO:0021004developmental stageinflorescence initiation stage
Sequence ? help Back to Top
Protein Sequence    Length: 354 aa     Download sequence    Send to blast
MQIPHRRYRW VKEWVSQELV VAGGPCVLYK WVREDRLAAL KAKDKKHGAE SATPEPNSEV  60
LFLCSYEGCG KTFFDAGALR KHAHVHGERQ YICHYENCGK KFLDSSKLKR HFLIHTGEKN  120
FVCPHEGCGK AFSLDFNLKA HMKTHSADNY HVCQYPECGR RFTQESKLRA HIRAQHEKAV  180
CLQNPGASAM NHSAIGEQHQ PPKPAKVSAT PPAPSAERPY VCPYDGCDKA YIHEYKLNLH  240
LKKEHPNHYQ DGGPQGAAPS KRSISKSSHR SRPDITARMP PAKVSKRKGG YAAPSPAVNL  300
PEEHLPEEQQ WPRKVMYEDD SEETEEEEGG NNVEDRWNYN RVASSDDEET EDEQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C4e-34641798120PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM5G885700
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM5G885700_P02
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0355350.0BT035535.1 Zea mays full-length cDNA clone ZM_BFb0068J12 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001131916.10.0transcription repressor TRM protein
SwissprotQ2V3L31e-101YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLB4FEJ70.0B4FEJ7_MAIZE; C2H2 transcription factor
STRINGGRMZM5G885700_P020.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Representative plantOGRP38561626
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-97C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Alexandrov NN, et al.
    Insights into corn genes derived from large-scale cDNA sequencing.
    Plant Mol. Biol., 2009. 69(1-2): p. 179-94
    [PMID:18937034]
  3. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  4. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]