PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GRMZM5G885700_P01

Common Name

LOC100193305

Organism

Zea mays

Taxonomic ID

4577

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea

Family

C2H2

Protein Properties

Length: 349aa MW: 39688.3 Da PI: 7.7979

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GRMZM5G885700_P01	genome	MaizeSequence	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.6	0.0004	64	86	3	23
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 C+ Cgk+F + L++H +H GRMZM5G885700_P01 64 CSyeGCGKTFFDAGALRKHAHVH 86 77779**************9887 PP
2	zf-C2H2	15.1	6.5e-05	91	115	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 y C+ +Cgk F ++s LkrH H GRMZM5G885700_P01 91 YICHyeNCGKKFLDSSKLKRHFLIH 115 89*******************8877 PP
3	zf-C2H2	21.8	4.8e-07	121	145	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 ++Cp Cgk Fs nLk H++tH GRMZM5G885700_P01 121 FVCPheGCGKAFSLDFNLKAHMKTH 145 89**********************9 PP
4	zf-C2H2	19.2	3.3e-06	151	176	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 ++C+ Cg++F++ s L+ Hir H GRMZM5G885700_P01 151 HVCQypECGRRFTQESKLRAHIRAqH 176 689999*****************888 PP
5	zf-C2H2	15.5	4.8e-05	215	240	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y+Cp C+k + + + L+ H+++ H GRMZM5G885700_P01 215 YVCPydGCDKAYIHEYKLNLHLKKeH 240 9**********************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	2.6E-13	58	88	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.0032	62	86	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.762	62	91	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	64	86	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	7.0E-8	65	115	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.3E-14	89	111	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	14.066	91	120	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.013	91	115	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	93	115	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.68E-14	102	155	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.1E-20	112	148	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	12.321	121	150	IPR007087	Zinc finger, C2H2
SMART	SM00355	4.3E-4	121	145	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	123	145	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.8E-8	150	173	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.697	151	180	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0047	151	176	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	4.47E-7	153	176	No hit	No description
PROSITE pattern	PS00028	0	153	176	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.2E-9	207	237	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.47E-7	210	237	No hit	No description
SMART	SM00355	0.0024	215	240	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.891	215	245	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	217	240	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 349 aa Download sequence Send to blast
MQIPHRRYRW VKEWVSQELV VAGGPCVLYK WVREDRLAAL KAKDKKHGAE SATPEPNSEV 60 LFLCSYEGCG KTFFDAGALR KHAHVHGERQ YICHYENCGK KFLDSSKLKR HFLIHTGEKN 120 FVCPHEGCGK AFSLDFNLKA HMKTHSADNY HVCQYPECGR RFTQESKLRA HIRAQHEKNP 180 GASAMNHSAI GEQHQPPKPA KVSATPPAPS AERPYVCPYD GCDKAYIHEY KLNLHLKKEH 240 PNHYQDGGPQ GAAPSKRSIS KSSHRSRPDI TARMPPAKVS KRKGGYAAPS PAVNLPEEHL 300 PEEQQWPRKV MYEDDSEETE EEEGGNNVED RWNYNRVASS DDEETEDEQ

Sequence ? help Back to Top

Protein Sequence Length: 349 aa Download sequence Send to blast

MQIPHRRYRW VKEWVSQELV VAGGPCVLYK WVREDRLAAL KAKDKKHGAE SATPEPNSEV  60
LFLCSYEGCG KTFFDAGALR KHAHVHGERQ YICHYENCGK KFLDSSKLKR HFLIHTGEKN  120
FVCPHEGCGK AFSLDFNLKA HMKTHSADNY HVCQYPECGR RFTQESKLRA HIRAQHEKNP  180
GASAMNHSAI GEQHQPPKPA KVSATPPAPS AERPYVCPYD GCDKAYIHEY KLNLHLKKEH  240
PNHYQDGGPQ GAAPSKRSIS KSSHRSRPDI TARMPPAKVS KRKGGYAAPS PAVNLPEEHL  300
PEEQQWPRKV MYEDDSEETE EEEGGNNVED RWNYNRVASS DDEETEDEQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ubd_C	4e-34	64	172	8	114	PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	GRMZM5G885700

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269\|PubMed:26961720}.
Uniprot	TISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269\|PubMed:26961720}.

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GRMZM5G885700_P01

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT087235	0.0	BT087235.1 Zea mays full-length cDNA clone ZM_BFb0009O15 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008681129.1	0.0	transcription repressor TRM protein isoform X1
Swissprot	Q2V3L3	1e-104	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	C4J8T8	0.0	C4J8T8_MAIZE; Uncharacterized protein
STRING	GRMZM5G885700_P02	0.0	(Zea mays)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G06634.1	1e-100	C2H2 family protein

Link Out ? help Back to Top
Phytozome	GRMZM5G885700_P01
Entrez Gene	100193305

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Alexandrov NN, et al. Insights into corn genes derived from large-scale cDNA sequencing. Plant Mol. Biol., 2009. 69(1-2): p. 179-94 [PMID:18937034] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]