PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GRMZM5G871347_P03

Common Name

Zm.86376

Organism

Zea mays

Taxonomic ID

4577

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea

Family

WRKY

Protein Properties

Length: 453aa MW: 48877 Da PI: 7.7374

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GRMZM5G871347_P03	genome	MaizeSequence	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	97.5	8.6e-31	319	377	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+a+d +++++tYeg+Hnh+ GRMZM5G871347_P03 319 ADGCQWRKYGQKMAKGNPCPRAYYRCTMAnGCPVRKQVQRCADDRSILITTYEGTHNHP 377 7*************************999*************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.5E-31	312	379	IPR003657	WRKY domain
PROSITE profile	PS50811	28.541	313	379	IPR003657	WRKY domain
SuperFamily	SSF118290	2.88E-27	315	379	IPR003657	WRKY domain
SMART	SM00774	5.4E-37	318	378	IPR003657	WRKY domain
Pfam	PF03106	1.2E-27	320	377	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0016021	Cellular Component	integral component of membrane
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 453 aa Download sequence Send to blast
MDKAHLGGGL LALDASPRPL GFLNLLSPPT SSPPFHRTRT MEADDVPAVP GNKGRRSIEV 60 DFFSDDKDKK SAAAAANDKK EDLTTINLLP GSNANDDDDD EAATRLRLPN DQDRQNRNTN 120 ELSAMQSELA RMNDENQRLR GMLTQVTTSY QALQMHLVAL MQARADGQPM MPPAVAQTLP 180 VTDAAAVMPS PRQFLGLGPA AAAEETSNSS TEVGSPRPSS SAGRRQDQQQ QAAERGDSPD 240 PADPSTTARQ LAQQQEASMR KARVSVRARS EAPIVRRSFC FSFLFLSFFL SFFYLSLFFP 300 FFLSFFLSSH MEDDRGQIAD GCQWRKYGQK MAKGNPCPRA YYRCTMANGC PVRKQVQRCA 360 DDRSILITTY EGTHNHPLPP AAVAMASTTS AAASMLLSGS MPSGDNFLAR AVLPCSSGMA 420 TISASAPFPT VTLDLTNGPA RCSSSRATAA APA

Sequence ? help Back to Top

Protein Sequence Length: 453 aa Download sequence Send to blast

MDKAHLGGGL LALDASPRPL GFLNLLSPPT SSPPFHRTRT MEADDVPAVP GNKGRRSIEV  60
DFFSDDKDKK SAAAAANDKK EDLTTINLLP GSNANDDDDD EAATRLRLPN DQDRQNRNTN  120
ELSAMQSELA RMNDENQRLR GMLTQVTTSY QALQMHLVAL MQARADGQPM MPPAVAQTLP  180
VTDAAAVMPS PRQFLGLGPA AAAEETSNSS TEVGSPRPSS SAGRRQDQQQ QAAERGDSPD  240
PADPSTTARQ LAQQQEASMR KARVSVRARS EAPIVRRSFC FSFLFLSFFL SFFYLSLFFP  300
FFLSFFLSSH MEDDRGQIAD GCQWRKYGQK MAKGNPCPRA YYRCTMANGC PVRKQVQRCA  360
DDRSILITTY EGTHNHPLPP AAVAMASTTS AAASMLLSGS MPSGDNFLAR AVLPCSSGMA  420
TISASAPFPT VTLDLTNGPA RCSSSRATAA APA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	3e-21	318	381	14	76	WRKY transcription factor 1
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	GRMZM5G871347

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Roots, leaves, shoots, flowers and siliques.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GRMZM5G871347_P03

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT084621	0.0	BT084621.2 Zea mays full-length cDNA clone ZM_BFb0146L18 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008673468.1	0.0	WRKY transcription factor 6 isoform X1
Swissprot	Q9C519	1e-93	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A3L6FH76	0.0	A0A3L6FH76_MAIZE; WRKY transcription factor 6
STRING	GRMZM5G871347_P03	0.0	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP5265	36	56
Representative plant	OGRP14	17	875

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	4e-72	WRKY family protein

Link Out ? help Back to Top
Phytozome	GRMZM5G871347_P03

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]