PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM2G380515_P04
Common Namepco068737, ZEAMMB73_981121
Organism
Zea mays
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family C2H2
Protein Properties Length: 374aa    MW: 43432.6 Da    PI: 8.2241
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM2G380515_P04genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2163.4e-057092123
                       EEETTTTEEESSHHHHHHHHHHT CS
            zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                       ++C+ Cg++F  + +Lk+H+++H
  GRMZM2G380515_P04 70 HRCQECGRCFQKPAHLKQHMQSH 92
                       79*******************98 PP
2zf-C2H223.81.1e-0798122123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        + Cp  dC+ s++rk++L+rH+ +H
  GRMZM2G380515_P04  98 FICPleDCPFSYKRKDHLNRHMLKH 122
                        78*********************99 PP
3zf-C2H214.88.2e-05127152123
                        EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                        ++C+   C+++Fs k +++rH +  H
  GRMZM2G380515_P04 127 FSCTldGCDMRFSMKADMQRHVKEiH 152
                        89999*****************9988 PP
4zf-C2H218.36.2e-06160184123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        ++C+   C+k+F+ +s Lk+H  +H
  GRMZM2G380515_P04 160 FVCKedGCNKVFRYSSKLKKHEESH 184
                        89*******************9988 PP
5zf-C2H212.10.00059251275223
                        EET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                        kC+   C   Fs+ksnL++H +  H
  GRMZM2G380515_P04 251 KCTfdGCEHFFSNKSNLTKHVKAcH 275
                        799999***************9955 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355222446IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.2E-66891IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.4847097IPR007087Zinc finger, C2H2
SMARTSM003550.0127092IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807294IPR007087Zinc finger, C2H2
SuperFamilySSF576672.51E-1082124No hitNo description
Gene3DG3DSA:3.30.160.606.1E-1192124IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.03798127IPR007087Zinc finger, C2H2
PfamPF000962.2E-598122IPR007087Zinc finger, C2H2
SMARTSM003551.9E-498122IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280100122IPR007087Zinc finger, C2H2
SuperFamilySSF576676.42E-8108159No hitNo description
Gene3DG3DSA:3.30.160.601.5E-6125154IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.572127157IPR007087Zinc finger, C2H2
SMARTSM003556.3E-4127152IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280129152IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.3E-8157184IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.471160184IPR007087Zinc finger, C2H2
SMARTSM003550.0033160184IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280162184IPR007087Zinc finger, C2H2
SMARTSM003555192217IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280194217IPR007087Zinc finger, C2H2
SMARTSM0035514220241IPR015880Zinc finger, C2H2-like
SuperFamilySSF576677.38E-8233292No hitNo description
PROSITE profilePS5015710.97250280IPR007087Zinc finger, C2H2
SMARTSM003550.17250275IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.604.5E-5251275IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280252275IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.4E-5276301IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501578.704281307IPR007087Zinc finger, C2H2
SMARTSM003556.5281307IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280283307IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MCSEVHVEGD ASVGQKGCKD IRRYKCEFCT VVRSKKCLIQ AHMVAHHKDE LDKSEIYNSD  60
GEKIVHEQEH RCQECGRCFQ KPAHLKQHMQ SHSHERLFIC PLEDCPFSYK RKDHLNRHML  120
KHEGKLFSCT LDGCDMRFSM KADMQRHVKE IHDSKNPHQF VCKEDGCNKV FRYSSKLKKH  180
EESHVKLDYV EVVCCEPGCM KMFRNVEYLR AHNQSCHQYV QCEICGEKHL KKNIKRHLQS  240
HDKVPSDGRM KCTFDGCEHF FSNKSNLTKH VKACHDQLKP FKCGIVGCGK AFTYKHVRDN  300
HETSGAHVYM EGDFEELDEQ LRARPRGGRK RKALTVETLT RKRVTISGEA SSLDDGVEYL  360
RWLLSGGDDS IDCQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A6e-177427519188PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D6e-177427519188PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1323331RPRGGRKRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Zm.669470.0ear| meristem| ovary| shoot| tassel
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM2G380515
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM2G380515_P04
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0383390.0BT038339.1 Zea mays full-length cDNA clone ZM_BFb0227N03 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008654475.10.0uncharacterized protein LOC100216772 isoform X2
SwissprotQ84MZ42e-94TF3A_ARATH; Transcription factor IIIA
TrEMBLK7V1N90.0K7V1N9_MAIZE; Pentatricopeptide repeat-containing protein
STRINGGRMZM2G380515_P020.0(Zea mays)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.27e-88transcription factor IIIA