PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM2G169149_P01
Common NameWRKY104, Zm.131363
Organism
Zea mays
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family WRKY
Protein Properties Length: 266aa    MW: 28958.6 Da    PI: 7.0204
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM2G169149_P01genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY924.7e-29102160259
                        --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
               WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                        +D y+WrKYGqK+ +++++prsY+rC++a +Cpvkkkv+rsa+d+ +++ tYegeHnhe
  GRMZM2G169149_P01 102 RDCYQWRKYGQKVTRDNPYPRSYFRCAYApSCPVKKKVQRSADDNLMLVATYEGEHNHE 160
                        79**************************99****************************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.807.2E-2896161IPR003657WRKY domain
PROSITE profilePS5081126.07396162IPR003657WRKY domain
SuperFamilySSF1182905.75E-2597161IPR003657WRKY domain
SMARTSM007744.5E-34101161IPR003657WRKY domain
PfamPF031064.2E-24103160IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009620Biological Processresponse to fungus
GO:0009751Biological Processresponse to salicylic acid
GO:0010200Biological Processresponse to chitin
GO:1900425Biological Processnegative regulation of defense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0006340anatomyadult vascular leaf
PO:0006505anatomycentral spike of ear inflorescence
PO:0009025anatomyvascular leaf
PO:0020040anatomyleaf base
PO:0001053developmental stagevascular leaf post-expansion stage
PO:0007003developmental stageIL.03 full inflorescence length reached stage
PO:0007006developmental stageIL.00 inflorescence just visible stage
PO:0007016developmental stagewhole plant flowering stage
PO:0007072developmental stageLP.18 eighteen leaves visible stage
Sequence ? help Back to Top
Protein Sequence    Length: 266 aa     Download sequence    Send to blast
MDSNGECSSP PTLSAALLPL FGPPPEPLPE SLEDKLRRVS EENRRLAAAL DAILADRSTP  60
RALATSSPSR GNAVAAAEPP RPKVRTVCAR AEPSDADANH LRDCYQWRKY GQKVTRDNPY  120
PRSYFRCAYA PSCPVKKKVQ RSADDNLMLV ATYEGEHNHE QRAQSEYVVT DASTSLHQAG  180
SSLPRSIISI DSSGRKKITI GLAADQRPPA DSNAGAAVGE IIVTPEFRKA LVDELVNLLT  240
NDSEFVEKLA SAVADRVMER IPGHIF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A2e-191011601472WRKY transcription factor 1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM2G169149
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Regulates negatively basal innate immunity and XA21-mediated defense against X.oryzae pv. oryzae (Xoo) (By similarity). {ECO:0000250|UniProtKB:Q6EPZ0, ECO:0000250|UniProtKB:Q6QHD1}.
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Regulates negatively basal innate immunity and XA21-mediated defense against X.oryzae pv. oryzae (Xoo) (PubMed:19825552, PubMed:21961049). {ECO:0000250|UniProtKB:Q6QHD1, ECO:0000269|PubMed:19825552, ECO:0000269|PubMed:21961049}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM2G169149_P01
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Might be activated by XA21 in the nucleus upon pathogen infection (PubMed:19825552). Induced by biotic elicitors (e.g. fungal chitin oligosaccharide) (PubMed:23462973). Induced by pathogen infection (e.g. M.grisea and X.oryzae pv. oryzae (Xoo)) (PubMed:16528562, PubMed:24093634). Accumulates after treatment with benzothiadiazole (BTH) and salicylic acid (SA) (PubMed:17601827, PubMed:16528562, PubMed:24093634). Transactivated by WRKY45 (PubMed:24093634). {ECO:0000269|PubMed:16528562, ECO:0000269|PubMed:17601827, ECO:0000269|PubMed:23462973, ECO:0000269|PubMed:24093634, ECO:0000303|PubMed:19825552}.
UniProtINDUCTION: Might be activated by XA21 in the nucleus upon pathogen infection (PubMed:20118235). Induced by biotic elicitors (e.g. fungal chitin oligosaccharide) (By similarity). Induced by pathogen infection (e.g. M.grisea and X.oryzae pv. oryzae (Xoo)). Accumulates after treatment with benzothiadiazole (BTH) and salicylic acid (SA) (PubMed:16528562). Transactivated by WRKY45 (By similarity). {ECO:0000250|UniProtKB:Q6EPZ0, ECO:0000269|PubMed:16528562, ECO:0000303|PubMed:20118235}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEU9560890.0EU956089.1 Zea mays clone 1557298 WRKY62 - superfamily of TFs having WRKY and zinc finger domains mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001147635.10.0uncharacterized protein LOC100281244
SwissprotB8BF912e-69WRK62_ORYSI; WRKY transcription factor WRKY62
SwissprotQ6EPZ02e-69WRK62_ORYSJ; WRKY transcription factor WRKY62
TrEMBLB6STM40.0B6STM4_MAIZE; WRKY transcription factor
STRINGGRMZM2G169149_P010.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP129212834
Representative plantOGRP1417875
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G31800.23e-36WRKY DNA-binding protein 18
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang Y,Wang L
    The WRKY transcription factor superfamily: its origin in eukaryotes and expansion in plants.
    BMC Evol. Biol., 2005. 5: p. 1
    [PMID:15629062]
  3. Wu KL,Guo ZJ,Wang HH,Li J
    The WRKY family of transcription factors in rice and Arabidopsis and their origins.
    DNA Res., 2005. 12(1): p. 9-26
    [PMID:16106749]
  4. Alexandrov NN, et al.
    Insights into corn genes derived from large-scale cDNA sequencing.
    Plant Mol. Biol., 2009. 69(1-2): p. 179-94
    [PMID:18937034]
  5. Chen X, et al.
    A conserved threonine residue in the juxtamembrane domain of the XA21 pattern recognition receptor is critical for kinase autophosphorylation and XA21-mediated immunity.
    J. Biol. Chem., 2010. 285(14): p. 10454-63
    [PMID:20118235]
  6. Peng Y,Bartley LE,Canlas P,Ronald PC
    OsWRKY IIa Transcription Factors Modulate Rice Innate Immunity.
    Rice (N Y), 2010. 3(1): p. 36-42
    [PMID:21961049]
  7. Park CJ,Ronald PC
    Cleavage and nuclear localization of the rice XA21 immune receptor.
    Nat Commun, 2012. 3: p. 920
    [PMID:22735448]
  8. Chujo T, et al.
    OsWRKY28, a PAMP-responsive transrepressor, negatively regulates innate immune responses in rice against rice blast fungus.
    Plant Mol. Biol., 2013. 82(1-2): p. 23-37
    [PMID:23462973]
  9. Nakayama A, et al.
    Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice.
    BMC Plant Biol., 2013. 13: p. 150
    [PMID:24093634]
  10. Hou Y, et al.
    JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators.
    BMC Plant Biol., 2015. 15: p. 286
    [PMID:26646110]
  11. Liu J, et al.
    Alternative Splicing of Rice WRKY62 and WRKY76 Transcription Factor Genes in Pathogen Defense.
    Plant Physiol., 2016. 171(2): p. 1427-42
    [PMID:27208272]