PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GRMZM2G011789_P01

Common Name

lec1, Lec1

Organism

Zea mays

Taxonomic ID

4577

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea

Family

NF-YB

Protein Properties

Length: 278aa MW: 29097.2 Da PI: 6.7994

Description

NF-YB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GRMZM2G011789_P01	genome	MaizeSequence	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NF-YB	171.4	9.8e-54	36	131	2	97
NF-YB 2 reqdrflPianvsrimkkvlPanakiskdaketvqecvsefisfvtseasdkcqrekrktingddllwalatlGfedyveplkvylkkyrel 93 reqdr++Pianv+rim++vlPa+akis+daket+qecvse+isf+t+ea+++cqre+rkti+++d+lwa++ lGf+dyvepl +yl++yre+ GRMZM2G011789_P01 36 REQDRLMPIANVIRIMRRVLPAHAKISDDAKETIQECVSEYISFITGEANERCQREQRKTITAEDVLWAMSRLGFDDYVEPLGAYLHRYREF 127 89****************************************************************************************** PP NF-YB 94 egek 97 eg+ GRMZM2G011789_P01 128 EGDA 131 *985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.20.10	1.6E-48	30	132	IPR009072	Histone-fold
SuperFamily	SSF47113	3.26E-37	38	134	IPR009072	Histone-fold
Pfam	PF00808	4.6E-25	42	105	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain
PRINTS	PR00615	4.4E-16	69	87	No hit	No description
PROSITE pattern	PS00685	0	72	88	IPR003956	Transcription factor, NFYB/HAP3, conserved site
PRINTS	PR00615	4.4E-16	88	106	No hit	No description
PRINTS	PR00615	4.4E-16	107	125	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046982	Molecular Function	protein heterodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MDSSSFLPAA GAENGSAAGG ANNGGAAQQH AAPAIREQDR LMPIANVIRI MRRVLPAHAK 60 ISDDAKETIQ ECVSEYISFI TGEANERCQR EQRKTITAED VLWAMSRLGF DDYVEPLGAY 120 LHRYREFEGD ARGVGLVPGA APSRGGDHHP HSMSPAAMLK SRGPVSGAAM LPHHHHHHDM 180 QMHAAMYGGT AVPPPAGPPH HGGFLMPHPQ GSSHYLPYAY EPTYGGEHAM AAYYGGAAYA 240 PGNGGSGDGS GSGGGGGSAS HTPQGSGGLE HPHPFAYK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5g49_A	2e-61	34	126	5	97	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT B-6
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	GRMZM2G011789

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed primarily during seed development. {ECO:0000269\|PubMed:12509518}.
Uniprot	TISSUE SPECIFICITY: Expressed in roots, flowers and developing siliques. Present in etiolated seedlings. {ECO:0000269\|PubMed:11250072, ECO:0000269\|PubMed:12509518, ECO:0000269\|PubMed:17322342}.

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Plays a role in the regulation of the embryogenesis. Involved in the abscisic acid (ABA) signaling pathway. {ECO:0000269\|PubMed:12509518, ECO:0000269\|PubMed:17322342}.

Function -- GeneRIF ? help Back to Top
Overexpression of ZmWRI1 results in an oil increase similar to overexpression of ZmLEC1 without affecting germination, seedling growth, or grain yield. [PMID: 20488892]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GRMZM2G011789_P01

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC210260	0.0	AC210260.5 Zea mays BAC clone CH201-44F4 from chromosome 5, complete sequence.
GenBank	AF410176	0.0	AF410176.1 Zea mays leafy cotyledon1 (Lec1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001105518.1	0.0	leafy cotyledon
Swissprot	Q84W66	3e-64	NFYB6_ARATH; Nuclear transcription factor Y subunit B-6
TrEMBL	Q94EJ7	0.0	Q94EJ7_MAIZE; LEC1 transcription factor1
STRING	GRMZM2G011789_P01	0.0	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP201	38	331
Representative plant	OGRP168	17	170

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G47670.2	6e-63	nuclear factor Y, subunit B6

Link Out ? help Back to Top
Phytozome	GRMZM2G011789_P01
Entrez Gene	542498

Publications ? help Back to Top
Shen B, et al. Expression of ZmLEC1 and ZmWRI1 increases seed oil production in maize. Plant Physiol., 2010. 153(3): p. 980-7 [PMID:20488892] Jia H,McCarty DR,Suzuki M Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression. Plant Physiol., 2013. 163(3): p. 1293-305 [PMID:24043445] Kim HU, et al. Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues. FEBS Open Bio, 2013. 4: p. 25-32 [PMID:24363987] Gnesutta N,Saad D,Chaves-Sanjuan A,Mantovani R,Nardini M Crystal Structure of the Arabidopsis thaliana L1L/NF-YC3 Histone-fold Dimer Reveals Specificities of the LEC1 Family of NF-Y Subunits in Plants. Mol Plant, 2017. 10(4): p. 645-648 [PMID:27871811] Li D, et al. MYB89 Transcription Factor Represses Seed Oil Accumulation. Plant Physiol., 2017. 173(2): p. 1211-1225 [PMID:27932421] Zhao H, et al. The Arabidopsis thaliana Nuclear Factor Y Transcription Factors. Front Plant Sci, 2016. 7: p. 2045 [PMID:28119722] Han JD, et al. Evolutionary Analysis of the LAFL Genes Involved in the Land Plant Seed Maturation Program. Front Plant Sci, 2017. 8: p. 439 [PMID:28421087]