PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GRMZM2G005066_P01

Common Name

C1, MYB1, ZEAMMB73_024037

Organism

Zea mays

Taxonomic ID

4577

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea

Family

MYB

Protein Properties

Length: 272aa MW: 28713.9 Da PI: 7.9431

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GRMZM2G005066_P01	genome	MaizeSequence	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	53.8	4.5e-17	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT Ed+ l+ +vk +G g W+ ++++ g++R++k+c++rw++yl GRMZM2G005066_P01 14 RGAWTSKEDDALAAYVKAHGEGKWREVPQKAGLRRCGKSCRLRWLNYL 61 89********************************************97 PP
2	Myb_DNA-binding	44.8	3e-14	74	112	7	47
HHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 7 eEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 eEd+ +++++++lG++ W++Ia +++ gRt++++k++w++ GRMZM2G005066_P01 74 EEDLMIIRLHRLLGNR-WSLIAGRLP-GRTDNEIKNYWNST 112 9*************.*****.*********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	3.8E-23	6	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	24.121	9	65	IPR017930	Myb domain
SuperFamily	SSF46689	6.64E-28	11	109	IPR009057	Homeodomain-like
SMART	SM00717	9.1E-13	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	3.8E-15	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	1.81E-9	16	61	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.6E-21	65	115	IPR009057	Homeodomain-like
PROSITE profile	PS51294	16.665	66	117	IPR017930	Myb domain
SMART	SM00717	1.2E-10	66	115	IPR001005	SANT/Myb domain
CDD	cd00167	6.39E-11	73	113	No hit	No description
Pfam	PF00249	1.4E-12	74	112	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 272 aa Download sequence Send to blast
MGRRACCAKE GVKRGAWTSK EDDALAAYVK AHGEGKWREV PQKAGLRRCG KSCRLRWLNY 60 LRPNIRRGNI SYDEEDLMII RLHRLLGNRW SLIAGRLPGR TDNEIKNYWN STLGRRAGAG 120 AGAGGSRVVI APDTGSHATP AATSGSGETG QKGAAPRADP DSAGTTTTSA AAVWAPKAVR 180 CTGGLFFFHR DTTPAHAGET ATPMAGGGLG GEAGSSEDCS SAASVSPLVG SQDEPCFSGD 240 GDCDWMDDVR ALASFLESDE DWLRCQTAGQ LA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	4e-24	14	117	7	108	B-MYB
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	GRMZM2G005066

Functional Description ? help Back to Top
Source	Description
UniProt	Controls the expression of genes involved in anthocyanin biosynthesis. Regulates the expression of at least 3 structural genes: chalcone synthase, dihydroflavonol reductase and flavonol O(3) glucosyltransferase. C1 acts as a trans-acting factor.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GRMZM2G005066_P01

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY237128	0.0	AY237128.1 Zea mays myb-related protein c1-I-2K1 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008659144.1	0.0	anthocyanin regulatory C1 protein-like
Swissprot	P10290	1e-144	MYBC_MAIZE; Anthocyanin regulatory C1 protein
TrEMBL	K7V9H9	0.0	K7V9H9_MAIZE; Anthocyanin regulatory C1 protein
STRING	GRMZM2G005066_P01	0.0	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP116	37	448
Representative plant	OGRP5	17	1784

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G13540.1	2e-54	myb domain protein 5

Link Out ? help Back to Top
Phytozome	GRMZM2G005066_P01
Entrez Gene	541757

Publications ? help Back to Top
Rabinowicz PD,Braun EL,Wolfe AD,Bowen B,Grotewold E Maize R2R3 Myb genes: Sequence analysis reveals amplification in the higher plants. Genetics, 1999. 153(1): p. 427-44 [PMID:10471724] Chen B,Wang X,Hu Y,Wang Y,Lin Z Ectopic expression of a c1-I allele from maize inhibits pigment formation in the flower of transgenic tobacco. Mol. Biotechnol., 2004. 26(3): p. 187-92 [PMID:15004287] Lai J, et al. Gene loss and movement in the maize genome. Genome Res., 2004. 14(10A): p. 1924-31 [PMID:15466290] Paz-Ares J,Ghosal D,Saedler H Molecular analysis of the C1-I allele from Zea mays: a dominant mutant of the regulatory C1 locus. EMBO J., 1990. 9(2): p. 315-21 [PMID:2303027] Cone KC,Burr FA,Burr B Molecular analysis of the maize anthocyanin regulatory locus C1. Proc. Natl. Acad. Sci. U.S.A., 1986. 83(24): p. 9631-5 [PMID:3025847] Paz-Ares J,Ghosal D,Wienand U,Peterson PA,Saedler H The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J., 1987. 6(12): p. 3553-8 [PMID:3428265] Scheffler B, et al. Molecular analysis of C1 alleles in Zea mays defines regions involved in the expression of this regulatory gene. Mol. Gen. Genet., 1994. 242(1): p. 40-8 [PMID:7904044] Franken P,Schrell S,Peterson PA,Saedler H,Wienand U Molecular analysis of protein domain function encoded by the myb-homologous maize genes C1, Zm 1 and Zm 38. Plant J., 1994. 6(1): p. 21-30 [PMID:7920701] Singer T,Gierl A,Peterson PA Three new dominant C1 suppressor alleles in Zea mays. Genet. Res., 1998. 71(2): p. 127-32 [PMID:9717435]