PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Vradi08g00970.1

Organism

Vigna radiata

Taxonomic ID

157791

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna

Family

E2F/DP

Protein Properties

Length: 510aa MW: 56340.5 Da PI: 5.1988

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Vradi08g00970.1	genome	SNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.7	7.4e-27	176	241	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Vradi08g00970.1 176 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 241 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	6.5E-29	173	243	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-34	176	241	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	7.48E-17	176	239	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	2.0E-24	178	241	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	4.18E-27	254	371	No hit	No description
CDD	cd14660	1.66E-44	254	371	No hit	No description
Pfam	PF16421	4.7E-29	257	369	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 510 aa Download sequence Send to blast
MSTAAGPPDR RASPPRGAAG TTVRPALKRH LAFVTKPPFA PPDDYHSFSS IDSRRLADEA 60 VVVRSPVSTS VSSLRSQIHL RGSRIWNVLF CVECDYMKRK GGMNDSEGES HTQKWSNSPG 120 YTNVSNITNS PFKTPVSAKG GRTQKAKASK EGRSCPPTPI SNAGSPSPLT PASSCRYDSS 180 LGLLTKKFIN LVKHAEDGIL DLNKAAETLE VQKRRIYDIT NVLEGIGLIE KKLKNRIHWK 240 GIESSTSGEV DGDISVLKEE VEKLSLEEQG LDDQIREMQE RLRKLSENEN NRKCLFVTED 300 DIKNLPCFQV FLLLILAYSC KQNETLIAIK APHGTTLEVP DPEEAVDYPQ RRYRIILRST 360 MGPIDVYLIS QFEEKFEEIN GAELPMIPLA SSSESNEQVM TEMVPAECSG KEFEPQTQLS 420 SHVYSDINAS QEFAGGMMKI VPSDVDNDAD YWLLSDADVS ITDMWRTDST VDWNGVDMLN 480 PDFGIISRPQ TPSSGFVEVP TPGANSNHK*

Sequence ? help Back to Top

Protein Sequence Length: 510 aa Download sequence Send to blast

MSTAAGPPDR RASPPRGAAG TTVRPALKRH LAFVTKPPFA PPDDYHSFSS IDSRRLADEA  60
VVVRSPVSTS VSSLRSQIHL RGSRIWNVLF CVECDYMKRK GGMNDSEGES HTQKWSNSPG  120
YTNVSNITNS PFKTPVSAKG GRTQKAKASK EGRSCPPTPI SNAGSPSPLT PASSCRYDSS  180
LGLLTKKFIN LVKHAEDGIL DLNKAAETLE VQKRRIYDIT NVLEGIGLIE KKLKNRIHWK  240
GIESSTSGEV DGDISVLKEE VEKLSLEEQG LDDQIREMQE RLRKLSENEN NRKCLFVTED  300
DIKNLPCFQV FLLLILAYSC KQNETLIAIK APHGTTLEVP DPEEAVDYPQ RRYRIILRST  360
MGPIDVYLIS QFEEKFEEIN GAELPMIPLA SSSESNEQVM TEMVPAECSG KEFEPQTQLS  420
SHVYSDINAS QEFAGGMMKI VPSDVDNDAD YWLLSDADVS ITDMWRTDST VDWNGVDMLN  480
PDFGIISRPQ TPSSGFVEVP TPGANSNHK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	5e-24	171	242	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Vradi08g00970.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015041	1e-145	AP015041.1 Vigna angularis var. angularis DNA, chromosome 8, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_014512110.1	0.0	transcription factor E2FA
Swissprot	Q9FNY0	1e-147	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A1S3V1C4	0.0	A0A1S3V1C4_VIGRR; transcription factor E2FA
STRING	XP_007145806.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1947	34	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-140	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]