PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Vang11g04060.1

Organism

Vigna angularis

Taxonomic ID

3914

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna

Family

AP2

Protein Properties

Length: 397aa MW: 43406.9 Da PI: 8.553

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Vang11g04060.1	genome	SNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	53.9	4.6e-17	89	138	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g Vang11g04060.1 89 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 138 78*****************......55**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	4.2E-9	89	138	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.54E-16	89	147	IPR016177	DNA-binding domain
CDD	cd00018	2.09E-12	90	214	No hit	No description
SMART	SM00380	2.0E-31	90	152	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.9E-17	90	146	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.596	90	146	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	11.087	135	212	IPR001471	AP2/ERF domain
SMART	SM00380	1.3E-8	168	218	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	6.0E-10	178	212	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.19E-8	179	214	IPR016177	DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 397 aa Download sequence Send to blast
MSTSTKNIDG RGQLYTKMLA NHKERVSKQF FPVEEADVAV ASGGGSSTFP RAHWVGVKFC 60 QSEALGAGKS VEVSQPMKKS RRGPRSRSSQ YRGVTFYRRT GRWESHIWDC GKQVYLGGFD 120 TAHAAARAYD RAAIKFRGVE ADINFNIEDY EDDLKQSSST CFADKALDFR GEAPNIEVYV 180 YLGLFDTEIE AAKAYDKAAI KCNGKEAVTN FDPSIYENEL NSGAESTGNG ADHNLDLSLG 240 NSSSKGGGNQ AFGNHHHGSN GGNHDQQVAA ESNWRNGGSK PKLVNILPKP CNRGNKDTQG 300 RDVHGESEAL RMLSQTHLHC PASSEMQRYG PYRSTGGESQ MLQNFAPIHP PNFHWQSGPP 360 HYLATAAASS GFPQQIRPSS QGWLQKNGFH TLMRPS*

Sequence ? help Back to Top

Protein Sequence Length: 397 aa Download sequence Send to blast

MSTSTKNIDG RGQLYTKMLA NHKERVSKQF FPVEEADVAV ASGGGSSTFP RAHWVGVKFC  60
QSEALGAGKS VEVSQPMKKS RRGPRSRSSQ YRGVTFYRRT GRWESHIWDC GKQVYLGGFD  120
TAHAAARAYD RAAIKFRGVE ADINFNIEDY EDDLKQSSST CFADKALDFR GEAPNIEVYV  180
YLGLFDTEIE AAKAYDKAAI KCNGKEAVTN FDPSIYENEL NSGAESTGNG ADHNLDLSLG  240
NSSSKGGGNQ AFGNHHHGSN GGNHDQQVAA ESNWRNGGSK PKLVNILPKP CNRGNKDTQG  300
RDVHGESEAL RMLSQTHLHC PASSEMQRYG PYRSTGGESQ MLQNFAPIHP PNFHWQSGPP  360
HYLATAAASS GFPQQIRPSS QGWLQKNGFH TLMRPS*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:23034631, ECO:0000269\|PubMed:7919989}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Vang11g04060.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:12893888, ECO:0000269\|PubMed:14555699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015034	1e-131	AP015034.1 Vigna angularis var. angularis DNA, chromosome 1, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017408128.1	0.0	PREDICTED: floral homeotic protein APETALA 2-like isoform X1
Swissprot	P47927	5e-80	AP2_ARATH; Floral homeotic protein APETALA 2
TrEMBL	A0A0L9TPF1	0.0	A0A0L9TPF1_PHAAN; Uncharacterized protein
TrEMBL	A0A0S3R515	0.0	A0A0S3R515_PHAAN; Uncharacterized protein
STRING	XP_007155905.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3784	34	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36920.2	4e-74	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Thamilarasan SK,Park JI,Jung HJ,Nou IS Genome-wide analysis of the distribution of AP2/ERF transcription factors reveals duplication and CBFs genes elucidate their potential function in Brassica oleracea. BMC Genomics, 2014. 15: p. 422 [PMID:24888752] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Ranocha P,Francoz E,Burlat V,Dunand C Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion. Plant Signal Behav, 2014. 9(11): p. e977734 [PMID:25531128] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Kazan K Diverse roles of jasmonates and ethylene in abiotic stress tolerance. Trends Plant Sci., 2015. 20(4): p. 219-29 [PMID:25731753] Prunet N, et al. SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. J. Exp. Bot., 2015. 66(21): p. 6905-16 [PMID:26269626] Xie W, et al. Exploring potential new floral organ morphogenesis genes of Arabidopsis thaliana using systems biology approach. Front Plant Sci, 2015. 6: p. 829 [PMID:26528302] Zumajo-Cardona C,Pabón-Mora N Evolution of the APETALA2 Gene Lineage in Seed Plants. Mol. Biol. Evol., 2016. 33(7): p. 1818-32 [PMID:27030733] Zhao Y, et al. An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design. Sci Rep, 2016. 6: p. 23890 [PMID:27033976] Gao R,Liu P,Irwanto N,Loh R,Wong SM Upregulation of LINC-AP2 is negatively correlated with AP2 gene expression with Turnip crinkle virus infection in Arabidopsis thaliana. Plant Cell Rep., 2016. 35(11): p. 2257-2267 [PMID:27473526] Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Dory M, et al. Kinase-Associated Phosphoisoform Assay: a novel candidate-based method to detect specific kinase-substrate phosphorylation interactions in vivo. BMC Plant Biol., 2016. 16(1): p. 204 [PMID:27655033] Wang P, et al. Expansion and Functional Divergence of AP2 Group Genes in Spermatophytes Determined by Molecular Evolution and Arabidopsis Mutant Analysis. Front Plant Sci, 2016. 7: p. 1383 [PMID:27703459] Sharma P, et al. Promoter Trapping and Deletion Analysis Show Arabidopsis thaliana APETALA2 Gene Promoter Is Bidirectional and Functions as a Pollen- and Ovule-Specific Promoter in the Reverse Orientation. Appl. Biochem. Biotechnol., 2017. 182(4): p. 1591-1604 [PMID:28130768] Kihira M, et al. Arabidopsis thaliana FLO2 is Involved in Efficiency of Photoassimilate Translocation, Which is Associated with Leaf Growth and Aging, Yield of Seeds and Seed Quality. Plant Cell Physiol., 2017. 58(3): p. 440-450 [PMID:28158741] Balanzà V, et al. Genetic control of meristem arrest and life span in Arabidopsis by a FRUITFULL-APETALA2 pathway. Nat Commun, 2018. 9(1): p. 565 [PMID:29422669] Dotto M,Gómez MS,Soto MS,Casati P UV-B radiation delays flowering time through changes in the PRC2 complex activity and miR156 levels in Arabidopsis thaliana. Plant Cell Environ., 2018. 41(6): p. 1394-1406 [PMID:29447428] Song C,Lee J,Kim T,Hong JC,Lim CO VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis. Planta, 2018. 247(6): p. 1439-1448 [PMID:29536220]