PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | 678352329 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Utricularia
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Family | AP2 | ||||||||
Protein Properties | Length: 453aa MW: 49801.5 Da PI: 8.0073 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 55.1 | 1.9e-17 | 147 | 197 | 1 | 56 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkklege 56 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++ge 678352329 147 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRGE 197 78*******************......55*************************997 PP | |||||||
2 | AP2 | 44 | 5.5e-14 | 239 | 289 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g 678352329 239 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEIEAARAYDKAAIKCNG 289 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF00847 | 1.6E-9 | 147 | 197 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 7.19E-16 | 147 | 204 | IPR016177 | DNA-binding domain |
CDD | cd00018 | 1.59E-11 | 147 | 203 | No hit | No description |
PROSITE profile | PS51032 | 17.556 | 148 | 204 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 2.2E-17 | 148 | 204 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 1.3E-31 | 148 | 210 | IPR001471 | AP2/ERF domain |
Pfam | PF00847 | 1.2E-9 | 239 | 289 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 1.56E-24 | 239 | 299 | No hit | No description |
SuperFamily | SSF54171 | 5.1E-17 | 239 | 299 | IPR016177 | DNA-binding domain |
Gene3D | G3DSA:3.30.730.10 | 1.7E-16 | 240 | 297 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 15.461 | 240 | 297 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 3.9E-32 | 240 | 303 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 3.9E-6 | 241 | 252 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 3.9E-6 | 279 | 299 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 453 aa Download sequence Send to blast |
MWDLNHEPLG EKGKGVLSGS DSGSSVVVVE DEQQTVVDCS RMSAKKKSGS GRKIFGFCVG 60 SEFEEEIDQS SNSKSLPVTR NFFPVGDADE VVVVGGEAAP NFPRAAHWVG IEFSNGGGGG 120 SSFLGRPAAV ETTRIKKNRR GPRSRSSQYR GVTFYRRTGR WESHIWDCGK QVYLGGFDTA 180 HAAARAYDRA AIKFRGEDAD INFCLEDYAE DLEKMTNLSK EEFVQVLRRQ STGFPRGSSK 240 YRGVTLHKCG RWEARMGQFL GKKYVYLGLF DTEIEAARAY DKAAIKCNGK EAVTNFDPSV 300 YQEELRAGGE SSSNNEPDHT LTLSLGNSIP IGESPSVCCS TEVDPRRRAA VPQPEQLSFG 360 ALQPRHGESQ MAFQLSHVTC HGPKEAGRAT EGHLVHAPFT LQGYNNIQHQ QQVRSLEHHH 420 NPWFASAASS GFPLLPRSVL QTKGSHHPAL RPP |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | 678352329 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011099111.1 | 1e-128 | floral homeotic protein APETALA 2 isoform X2 | ||||
Swissprot | P47927 | 1e-107 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A2G9G0S3 | 1e-123 | A0A2G9G0S3_9LAMI; Uncharacterized protein | ||||
STRING | XP_007155905.1 | 1e-117 | (Phaseolus vulgaris) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA2019 | 23 | 65 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-104 | AP2 family protein |