PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Tp57577_TGAC_v2_mRNA38833 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
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Family | E2F/DP | ||||||||
Protein Properties | Length: 378aa MW: 42665.7 Da PI: 8.4293 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 76.8 | 2.1e-24 | 18 | 83 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ + ++v l+++a +L v +rRRiYDi+NVLe+++++++k+kn+++wkg Tp57577_TGAC_v2_mRNA38833 18 RKQKSLGLLCTNFLSLYNRDDVRVVGLDDAAGRL---GV--ERRRIYDIVNVLESIGVLQRKAKNQYTWKG 83 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 75.6 | 5.1e-24 | 159 | 239 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL lltq+f+kl+ +s+ ++++l+++a+ L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g Tp57577_TGAC_v2_mRNA38833 159 RREKSLALLTQNFVKLFVCSNLEMISLDDAARLLLGDaynssTMRTKVRRLYDIANVLTSMNLIEKthttdTRKPAFRWLG 239 689*******************************************************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 8.6E-26 | 14 | 84 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.38E-16 | 17 | 81 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.3E-29 | 18 | 83 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-20 | 19 | 83 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 4.8E-23 | 156 | 241 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 3.7E-29 | 159 | 239 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.9E-19 | 161 | 239 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.62E-13 | 161 | 240 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 378 aa Download sequence Send to blast |
MASSSDPPPS SRHHTYDRKQ KSLGLLCTNF LSLYNRDDVR VVGLDDAAGR LGVERRRIYD 60 IVNVLESIGV LQRKAKNQYT WKGFGAIPVA LQELKEEGLW QNSQEGGNED TKVSDEEDED 120 ESLSQPTGSQ GESLSQPTGC QNDILNPNSA FPRSLKNDRR EKSLALLTQN FVKLFVCSNL 180 EMISLDDAAR LLLGDAYNSS TMRTKVRRLY DIANVLTSMN LIEKTHTTDT RKPAFRWLGL 240 KGKTWNEASL SRKRAFGNDV TNISFGRNRT DSFMGGDFSQ NLKKQKTMEN DSGLCQDDKN 300 NMKQKQSYQF GPFAPAYVSK AGTSENKVKQ VHDWESLATE HCPQYQNQAL KELYSHYMEA 360 WKSWYSEVAG KRSTQVL* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 8e-42 | 18 | 231 | 4 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Tp57577_TGAC_v2_mRNA38833 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013457830.1 | 0.0 | E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 1e-122 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A2K3NVN5 | 0.0 | A0A2K3NVN5_TRIPR; E2F transcription factor-like E2Fe-like protein | ||||
STRING | AES91128 | 0.0 | (Medicago truncatula) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3668 | 33 | 66 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-114 | DP-E2F-like 1 |
Link Out ? help Back to Top | |
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Phytozome | Tp57577_TGAC_v2_mRNA38833 |
Publications ? help Back to Top | |||
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