PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA13516
Organism
Trifolium pratense
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family AP2
Protein Properties Length: 651aa    MW: 73080.9 Da    PI: 6.6503
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA13516genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP236.11.6e-11285341155
                        AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                                s+++GV++++++gr++A+++d  ++  g  rk  + g ++ +e+Aa+a++ a++k++g
  Tp57577_TGAC_v2_mRNA13516 285 SQFRGVTRHRWTGRYEAHLWDnSCKkEGqTRKGRQ-GGYDLEEKAARAYDLAALKYWG 341
                                789******************77776664346655.77***9**************98 PP
2AP2414.8e-13400449355
                        AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                                y+GV+++++ grW A+I  +     ++  +lg+f t eeAa+ ++ a+ k++g
  Tp57577_TGAC_v2_mRNA13516 400 YRGVTRHHQHGRWQARIGRVAG---NRDLYLGTFSTQEEAAESYDVAAIKFRG 449
                                9***************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000182.02E-18285349No hitNo description
SuperFamilySSF541711.11E-13285350IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.109.4E-12286350IPR001471AP2/ERF domain
PROSITE profilePS5103216.911286349IPR001471AP2/ERF domain
PfamPF008477.2E-9286341IPR001471AP2/ERF domain
SMARTSM003809.6E-21286355IPR001471AP2/ERF domain
SuperFamilySSF541711.5E-16398459IPR016177DNA-binding domain
CDDcd000184.17E-24398459No hitNo description
Gene3DG3DSA:3.30.730.101.8E-17399458IPR001471AP2/ERF domain
SMARTSM003805.9E-32399463IPR001471AP2/ERF domain
PROSITE profilePS5103218.953399457IPR001471AP2/ERF domain
PfamPF008478.2E-9400449IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007276Biological Processgamete generation
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0042127Biological Processregulation of cell proliferation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 651 aa     Download sequence    Send to blast
MMNDSNTSDD GNNHNWLGFS LSPYQMGEIT SESDLSHNPN NHHHYYHHDN QVSSSAVVPS  60
NFYMSPSMCY GVGQNSNSFH SSLSMMPLNS DGSLCIMEEA LTRSQSHVMM PPKLEDFLGG  120
ATMETHHEYE GHERETMALS LDSIYYNNNV EQQDHSSYYS ELACHGMYQQ APLLEQEENK  180
EDNIFCFKNF VAPRDYSLEQ HHHQVNNNVV DDGSVGTVNG CGELQSLTLS MSPGSQSSCV  240
TVPTQISSSG NDSMVVEAKK RGNGKVGKKQ PVHRKSIDTF GQRTSQFRGV TRHRWTGRYE  300
AHLWDNSCKK EGQTRKGRQG GYDLEEKAAR AYDLAALKYW GPSTHINFPL EKYQIELEEM  360
NNMNRQEYVA HLRRYRHWLT FFFLLVCRKS SGFSRGASMY RGVTRHHQHG RWQARIGRVA  420
GNRDLYLGTF STQEEAAESY DVAAIKFRGL NAVTNFDMSK YNVEKIMASN TLLVGEHARR  480
TTKKIKDCEE PKPEAKECNN NVVVTNQITN GEEIEAVNNN ETNNWNQSPQ QESNTCDQKT  540
VKFGNFSMSL QDIIGIDSVG GSSQVLVDDD STNKMKRTHF SNSSSLVTSL SSSRECSPDN  600
KSTGPTMLFP KPPIGSKNLS PIVTNVGSWF PSSSTISMPH FPVFAAWSDA *
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00088SELEXTransfer from AT4G37750Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA13516
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024632987.10.0AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-142ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A2K3MV980.0A0A2K3MV98_TRIPR; Ap2-like ethylene-responsive transcription factor ant-like protein
STRINGXP_004498950.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF91634114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-143AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]