PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010537520.1
Organism
Tarenaya hassleriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
Family HD-ZIP
Protein Properties Length: 725aa    MW: 78990.8 Da    PI: 6.682
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010537520.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.72.7e-203893156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++ +++t++q+++Le+ F+++++p++++r +L+++lgL  rq+k+WFqNrR+++k
  XP_010537520.1 38 KKRYHRHTAHQIQRLEATFKECPHPDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 93
                    688999***********************************************998 PP
2START165.83e-522394582205
                     HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetle 83 
                     +a +a++el+++++ +ep+W++     +++n   + ++f++  +       ++ea+r s+vv+m++  lv  ++d   +W e ++    + +tl+
  XP_010537520.1 239 VAVTAMEELLRLIQTNEPLWTRTDacrDILNLGSYESIFPRPSSrgknpnIRTEASRYSAVVFMNASALVDMFMDCI-KWAELFPtivaASKTLA 332
                     6889******************999**999999999999886668899999**************************.99999999999****** PP

                     EECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE CS
           START  84 vissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvd 171
                     vissg      g l+lm+ elq+lsplv+ R+f ++Ry++q ++g+w++v +S + +q+++      Ra +lpSg+li++++ng+skvtwvehvd
  XP_010537520.1 333 VISSGmggaqgGSLHLMYEELQVLSPLVAtREFCMLRYCQQIEQGTWAVVNISYELPQFVSH----SRAYRLPSGCLIQDMPNGYSKVTWVEHVD 423
                     ************************************************************95....89999************************ PP

                     --SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXX CS
           START 172 lkgrlp.hwllrslvksglaegaktwvatlqrqce 205
                     ++++ p h+++r +++sg+a+ga +wva lqr  e
  XP_010537520.1 424 VEEKEPiHEMYRETIHSGQAFGAERWVAILQRMSE 458
                     *******************************9877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.8E-221297IPR009057Homeodomain-like
SuperFamilySSF466892.72E-202295IPR009057Homeodomain-like
PROSITE profilePS5007118.0913595IPR001356Homeobox domain
SMARTSM003891.5E-193699IPR001356Homeobox domain
PfamPF000466.4E-183893IPR001356Homeobox domain
CDDcd000861.18E-193896No hitNo description
PROSITE patternPS0002707093IPR017970Homeobox, conserved site
PROSITE profilePS5084847.293229462IPR002913START domain
SuperFamilySSF559612.2E-32230461No hitNo description
CDDcd088753.33E-107233458No hitNo description
SMARTSM002344.6E-45238459IPR002913START domain
PfamPF018527.1E-45239458IPR002913START domain
Gene3DG3DSA:3.30.530.202.8E-11282427IPR023393START-like domain
SuperFamilySSF559613.96E-20482717No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 725 aa     Download sequence    Send to blast
MKMDFVGGGG GSGSGSGGDG GSQRHEGGVG GSDAERKKKR YHRHTAHQIQ RLEATFKECP  60
HPDEKQRLQL SRELGLAPRQ IKFWFQNRRT QMKSQHERAD NCALRVENDK IRCENIAIRE  120
ALKNAICPSC GGPPVSEDPY FDEQNLRMEN AQLREELERV SGIAAKCIGR PISQLPPLHP  180
MHISPLDLSM ASLGGQGMAG GPSLDFDLLP GSCSMAIPNL PSQPNLVLSD MDKPLMTDVA  240
VTAMEELLRL IQTNEPLWTR TDACRDILNL GSYESIFPRP SSRGKNPNIR TEASRYSAVV  300
FMNASALVDM FMDCIKWAEL FPTIVAASKT LAVISSGMGG AQGGSLHLMY EELQVLSPLV  360
ATREFCMLRY CQQIEQGTWA VVNISYELPQ FVSHSRAYRL PSGCLIQDMP NGYSKVTWVE  420
HVDVEEKEPI HEMYRETIHS GQAFGAERWV AILQRMSERF ASLLVSGTSS RDLGGVIPSV  480
DGKRSMMRLA QRMVSNFCLS AGSSNNSRST VVSGLNEVGV RVTAHKSPEP NGMILCAATT  540
FWLPISPQNI FNFLKDERTR PQWDVLSNGN AVQEVAHIAN GSHPGNCISV LRAFNASQNN  600
MLILQESCID SSGALVVYSP VDLSALHIAM SGEDPSYIPL LPSGFTISPD CSSSRIATDD  660
ENCASTSSGR SSSGGVGGSL ITVAFQIMVS SLPSAKLNME SVTTVNNLIN TTVHQIKTAL  720
NCPTA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010537520.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010537520.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A178W9A40.0A0A178W9A4_ARATH; HDG11
STRINGXP_010537520.10.0(Tarenaya hassleriana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30042665
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]