PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010537276.1

Organism

Tarenaya hassleriana

Taxonomic ID

28532

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

LSD

Protein Properties

Length: 176aa MW: 18693.8 Da PI: 8.4418

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010537276.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	37.3	4.5e-12	7	29	1	23
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCd 23 C+gCr +L YPrGA++V+CalC XP_010537276.1 7 CHGCRSILLYPRGATNVCCALCS 29 **********************7 PP
2	zf-LSD1	42.3	1.2e-13	51	74	1	24
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdt 24 CggCrt+L+Y rGA sVRC++C+t XP_010537276.1 51 CGGCRTMLMYSRGANSVRCSCCQT 74 ***********************8 PP
3	zf-LSD1	47.1	3.8e-15	90	114	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 Cg+Crt+L+YP+GA+sV+Ca+C+ V XP_010537276.1 90 CGHCRTTLMYPYGASSVKCAICQYV 114 ***********************87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	1.2E-11	4	34	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	5.2E-10	7	31	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	4.6E-17	48	78	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.5E-11	51	74	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	7.5E-14	87	117	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	5.7E-14	90	114	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 176 aa Download sequence Send to blast
MQDQLVCHGC RSILLYPRGA TNVCCALCSM INIVPPPPPV RAGVDMAHII CGGCRTMLMY 60 SRGANSVRCS CCQTLNLVPA HTNQVAHINC GHCRTTLMYP YGASSVKCAI CQYVTNVNMG 120 NARPHIPANR PNGTATPGTM PSTSTTQTVV VENPMSVDES GKLVSNVVVG VTTDKK

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010537276.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010537276.1	1e-125	PREDICTED: protein LSD1 isoform X1
Refseq	XP_010537282.1	1e-125	PREDICTED: protein LSD1 isoform X1
Refseq	XP_010537289.1	1e-125	PREDICTED: protein LSD1 isoform X1
Swissprot	P94077	1e-85	LSD1_ARATH; Protein LSD1
TrEMBL	A0A1R3HTZ6	2e-91	A0A1R3HTZ6_9ROSI; Snf7
STRING	XP_010537299.1	1e-121	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5345	26	50

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	4e-88	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]