PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010535712.1

Organism

Tarenaya hassleriana

Taxonomic ID

28532

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

E2F/DP

Protein Properties

Length: 458aa MW: 50133 Da PI: 4.2622

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010535712.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	74.5	1.1e-23	136	201	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL++lt+++++l++++e+gi++l+e+a L +v k+RR+YDi+NVLe+++l+ek+ kn+i+wkg XP_010535712.1 136 RYNSSLGVLTKNLVNLIKHVEDGILDLREAAAIL---QV--KKRRLYDITNVLEGIGLMEKTVKNKIQWKG 201 6789****************************...99..9*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.2E-24	134	203	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	6.9E-29	136	201	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	5.85E-15	136	199	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	3.3E-21	138	201	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	5.18E-42	212	318	No hit	No description
SuperFamily	SSF144074	4.97E-29	214	318	No hit	No description
Pfam	PF16421	1.1E-30	217	316	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 458 aa Download sequence Send to blast
MSESQKPSKS PPPKRQLHPA VFSMRSAAFG DYHRFDATKR GGASDQETEA IVFKSPSQVR 60 QALSLHQHPK PETDTANRTP ESNELSTEEE EEEEEVGKSN DSIHTPVSEE VGKAQNSSDS 120 KKGSPGDNFG QAGTSRYNSS LGVLTKNLVN LIKHVEDGIL DLREAAAILQ VKKRRLYDIT 180 NVLEGIGLME KTVKNKIQWK GLDVSSPEET AESIAKLQEE TQNLTAEETK LDEQIREMQE 240 KISSLSEDEN NKKLLFVTKE DINSIPSFQN ETLIAVSALP GTMLEVPDPD EGGDSTQRRY 300 SICLRSTMGP IDVYLVSEFE ELSSRVMLAG ENGADAALDL PSTSGSHENQ ETATDNNMES 360 QEQGVAQIMC SDNELDDFVN GILNTVPSDW DAGMDYWLLS EADDVSITER WLSEPEVNLN 420 PSSSHDQESA PPGGTTLQQP QPPSSPKAEH SAAKSTGS

Sequence ? help Back to Top

Protein Sequence Length: 458 aa Download sequence Send to blast

MSESQKPSKS PPPKRQLHPA VFSMRSAAFG DYHRFDATKR GGASDQETEA IVFKSPSQVR  60
QALSLHQHPK PETDTANRTP ESNELSTEEE EEEEEVGKSN DSIHTPVSEE VGKAQNSSDS  120
KKGSPGDNFG QAGTSRYNSS LGVLTKNLVN LIKHVEDGIL DLREAAAILQ VKKRRLYDIT  180
NVLEGIGLME KTVKNKIQWK GLDVSSPEET AESIAKLQEE TQNLTAEETK LDEQIREMQE  240
KISSLSEDEN NKKLLFVTKE DINSIPSFQN ETLIAVSALP GTMLEVPDPD EGGDSTQRRY  300
SICLRSTMGP IDVYLVSEFE ELSSRVMLAG ENGADAALDL PSTSGSHENQ ETATDNNMES  360
QEQGVAQIMC SDNELDDFVN GILNTVPSDW DAGMDYWLLS EADDVSITER WLSEPEVNLN  420
PSSSHDQESA PPGGTTLQQP QPPSSPKAEH SAAKSTGS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-19	135	202	6	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010535712.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019057791.1	0.0	PREDICTED: transcription factor E2FB-like
Swissprot	Q9FV71	1e-145	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A1J3DY82	1e-153	A0A1J3DY82_NOCCA; Transcription factor E2FB (Fragment)
TrEMBL	A0A1J3K7H5	1e-153	A0A1J3K7H5_NOCCA; Transcription factor E2FB
STRING	XP_010535712.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM808	28	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-140	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]