PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010528612.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
Family ARF
Protein Properties Length: 825aa    MW: 91300.7 Da    PI: 6.6594
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010528612.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.13.4e-23127228199
                     EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSS CS
              B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrs 88 
                     f+k+lt sd++++g +++p++ ae+        ++++++  +l  +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   +++
  XP_010528612.1 127 FCKTLTASDTSTHGGFSVPRRAAEKVfppldysQQPPAQ--ELLAKDLHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVIFI--RNE 217
                     99*****************************85444444..8************************************************..568 PP

                     EE..EEEEE-S CS
              B3  89 efelvvkvfrk 99 
                     + +l+++++r+
  XP_010528612.1 218 KNQLLLGIRRA 228
                     8889**99986 PP

2Auxin_resp116.72e-38253336183
      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                     aahaast+s F+v+Y+Pras+s+Fv++++k+ ka+  +++svGmRf+m fete+ss rr++Gt++g+sdldpvrWpnS+Wrs+k
  XP_010528612.1 253 AAHAASTNSCFTVFYHPRASPSDFVIPLSKYIKAVFhTRISVGMRFRMLFETEESSVRRYMGTITGISDLDPVRWPNSHWRSVK 336
                     79*******************************986599******************************************985 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.44E-48112256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.2E-40120242IPR015300DNA-binding pseudobarrel domain
CDDcd100171.73E-20126227No hitNo description
PfamPF023623.4E-21127228IPR003340B3 DNA binding domain
PROSITE profilePS5086312.041127229IPR003340B3 DNA binding domain
SMARTSM010198.1E-23127229IPR003340B3 DNA binding domain
PfamPF065071.2E-33253336IPR010525Auxin response factor
SuperFamilySSF542774.45E-7722796No hitNo description
PROSITE profilePS5174523.382722806IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 825 aa     Download sequence    Send to blast
MKLSASGLGH QGHEGENKCL NSELWHACAG PLVSLPSSGS RVVYFPQGHS EQVAATTNKE  60
VDGHIPNYPS LPPQLISQLH NVTMHADVET DEVYAQMTLQ PLTPEEQKET FIPIELGIPS  120
KQPSNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDYSQ QPPAQELLAK DLHDVEWKFR  180
HIFRGQPKRH LLTTGWSVFV SAKRLVAGDS VIFIRNEKNQ LLLGIRRAIR PQTIIPSSVL  240
SSDSMHIGLL AAAAHAASTN SCFTVFYHPR ASPSDFVIPL SKYIKAVFHT RISVGMRFRM  300
LFETEESSVR RYMGTITGIS DLDPVRWPNS HWRSVKVGWD ESTAGERQPR VSLWEIEPLT  360
TFPMYPSLFP LRLKRPWHAG PSSLHDSRGD LTSGLSWLRG GAGEQGLLPL NFSSVGMVPW  420
MQQRLDLGLL GATDHNQQYQ AMLAAGLQNM SGGDPLRQQP FVQLQEEPHH QYLQQSGGHN  480
SDLLLQQQQQ QLPRHLLEAQ TRQMLTENIP HQTIRQEVSN QPAGQPHQPN HAYLNALKMQ  540
NGHLQQWQPS DLPSASFMKA DFTDSNHKFA TTVTPIQQNS AAPASGSGDG SNLLSFSITG  600
QPLLAEQLPS QAWSPKHAHS AANAFSEPLP LQQGYARKGT ALELGNSNPN PHSPSIFGVD  660
SDSGLFLPTT VPRYAPLPAA EADASSMSLT DSGFQNSLYS CMQDAPELLH GAGDINASNQ  720
IKNFVKVYKS GSVGRSLDIS RFSSYNELRE ELGKMFGIEG LLEDPLRSGW QLVFVDKEND  780
ILLLGDDPWE SFVNNVWYIK ILSPEDVQKM GQQGDGSFLQ NPNHH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1562035751388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010528612.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010528612.10.0PREDICTED: auxin response factor 8-like
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLR0GF160.0R0GF16_9BRAS; Auxin response factor
STRINGXP_010528612.10.0(Tarenaya hassleriana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM13442894
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]