PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_010527132.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
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Family | E2F/DP | ||||||||
Protein Properties | Length: 486aa MW: 53819.8 Da PI: 4.6524 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85 | 5.9e-27 | 175 | 240 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+ lt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg XP_010527132.1 175 RYDSSLGFLTKKFINLIKQAEDGMLDLNKAAEKL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 240 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.8E-29 | 172 | 242 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.72E-17 | 175 | 238 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.8E-34 | 175 | 240 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.6E-24 | 177 | 240 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 8.11E-34 | 253 | 357 | No hit | No description |
CDD | cd14660 | 4.37E-49 | 253 | 357 | No hit | No description |
Pfam | PF16421 | 2.5E-34 | 256 | 355 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 486 aa Download sequence Send to blast |
MSDGARSSLF PAPPAPGPPQ PQHPPSSPAP SPKTSAPVMP PIRRHLAFAS TKPPFHPSDE 60 YHRFVPCPAS NTDDNCVVNG FRVADQEEDA IVVRSPALKR KSTMDSGDVQ SNNGFTSPCF 120 TSLSNTPYQT PVSEKRGRVI NRSKASKGNR STPQTPISNA VAASPATLTP TGSCRYDSSL 180 GFLTKKFINL IKQAEDGMLD LNKAAEKLEV QKRRIYDITN VLEGIGLIEK KLKNRIQWKG 240 FDARRPGDMD ADVSVLQAEI ENLTVEEKTL DNQIREMQEK LRDLSENENN QKWLFVTEED 300 IKSLPCFQNE TLIAIKAPHG TTLEVPDPDE AADYPQRRYR IILRSTMGPI DVYLVSQFEE 360 KYEDANGADP QGNLPIASSS GSNENNDIET FTIDNTRSEV QPQVTHAQSS TSDLDSLQDQ 420 VGGMLKITPS DVENDDYWLL SGTELSMTEY WKTDFGIDWD FGTADISTAT PRNETPEIPS 480 VESSRR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-22 | 170 | 240 | 2 | 73 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_010527132.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_010527132.1 | 0.0 | PREDICTED: transcription factor E2FA-like isoform X1 | ||||
Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | V4MAR9 | 0.0 | V4MAR9_EUTSA; Uncharacterized protein | ||||
STRING | XP_010527132.1 | 0.0 | (Tarenaya hassleriana) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 0.0 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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