PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG036926t1
Common NameTCM_036926
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family ARR-B
Protein Properties Length: 626aa    MW: 68078.9 Da    PI: 6.6881
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG036926t1genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like90.51.5e-28202255155
           G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                       kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+ Lt+e+v+SHLQkYRl
  Thecc1EG036926t1 202 KPRVVWSVELHRKFVAAVNQL-GIDKAVPKKILELMNVEKLTRENVASHLQKYRL 255
                       79*******************.********************************8 PP
2Response_reg77.93.5e-26201281109
                       EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHH CS
      Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealk 91 
                       vl vdD+p+ + ll+++l++ +y +v++++++  al+ll+e++  +Dl++ D+ mp+mdG++ll++   e  +lp+i+++a+g+ +++ + + 
  Thecc1EG036926t1  20 VLAVDDDPTCLLLLETLLRRCQY-NVTTTSQAITALKLLRENKnkFDLVISDVHMPDMDGFKLLEHVGLEM-DLPVIMLSANGDTKLVMKGIT 110
                       799********************.***************888888**********************6644.8******************** PP

                       TTESEEEESS--HHHHHH CS
      Response_reg  92 aGakdflsKpfdpeelvk 109
                        Ga d+l Kp+ +eel +
  Thecc1EG036926t1 111 HGACDYLLKPVRIEELQN 128
                       ***************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363925.0E-1721602IPR017053Response regulator B-type, plant
SuperFamilySSF521726.26E-3617140IPR011006CheY-like superfamily
Gene3DG3DSA:3.40.50.23003.3E-4217141No hitNo description
SMARTSM004481.1E-3218130IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.16819134IPR001789Signal transduction response regulator, receiver domain
PfamPF000721.1E-2320128IPR001789Signal transduction response regulator, receiver domain
CDDcd001562.65E-2321133No hitNo description
PROSITE profilePS5129412.451199258IPR017930Myb domain
SuperFamilySSF466894.3E-20199259IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.5E-30200260IPR009057Homeodomain-like
TIGRFAMsTIGR015571.7E-25202255IPR006447Myb domain, plants
PfamPF002495.8E-7204254IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009414Biological Processresponse to water deprivation
GO:0010082Biological Processregulation of root meristem growth
GO:0010380Biological Processregulation of chlorophyll biosynthetic process
GO:0031537Biological Processregulation of anthocyanin metabolic process
GO:0048367Biological Processshoot system development
GO:0080022Biological Processprimary root development
GO:0080036Biological Processregulation of cytokinin-activated signaling pathway
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 626 aa     Download sequence    Send to blast
MTVERAISEP KDQFPVGMRV LAVDDDPTCL LLLETLLRRC QYNVTTTSQA ITALKLLREN  60
KNKFDLVISD VHMPDMDGFK LLEHVGLEMD LPVIMLSANG DTKLVMKGIT HGACDYLLKP  120
VRIEELQNIW QHVVRRKKFD RKDGDNSGSQ DKPHIDNGGA AGMGSVDQNG KLNKKRKDQN  180
EDEDEEHDEN GHDNEDPSTQ KKPRVVWSVE LHRKFVAAVN QLGIDKAVPK KILELMNVEK  240
LTRENVASHL QKYRLYLKRI SCVANQQANM AAALGSADST YLRMGPLNGL GNFHTLAGSD  300
QLHNAALRSF PPSGVLGRLN TPAGLGVRGL PSPGMIQLGH VQNSGNTSND QSKLQSFVIP  360
GNHNANTLQG MPMSLELDQL QNNKGVSHIG ELPTAANTTV FPVSGSLMDA RISGCSNNPL  420
LGVTSNSLML EGSSQQTTLH PSNLRDSVST MGFQNGNTLS DFTSIATASN QLQCSKADLQ  480
CQASPTSCNA GQIIRSAPPE WNAPYHSNVM CCSINSSIPV NGAMVPLGQC LDQNNPNFHR  540
NMDLDSIAPS NFVDPKSLKR SEGFNSAMEP AVIQKEGYFQ PRPQGGYNVG SLEDLASAMM  600
KEGPDTRKLA DGDFGCNGYS HRTCI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A9e-26198261164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455). {ECO:0000250|UniProtKB:Q940D0, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:20605455}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007011750.20.0PREDICTED: two-component response regulator ARR12 isoform X2
SwissprotP625981e-155ARR12_ARATH; Two-component response regulator ARR12
TrEMBLA0A061GQF80.0A0A061GQF8_THECC; Two-component response regulator
STRINGEOY293690.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19812879
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25180.11e-145response regulator 12
Publications ? help Back to Top
  1. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  2. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  3. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  4. Kim HJ,Kieber JJ,Schaller GE
    The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.
    Plant Signal Behav, 2013. 8(12): p. e26434
    [PMID:24675172]
  5. Choi SH, et al.
    Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis.
    Sci Rep, 2014. 4: p. 7197
    [PMID:25425016]
  6. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  7. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  8. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  9. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  10. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  11. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  12. Dai X, et al.
    ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
    J Integr Plant Biol, 2017. 59(10): p. 747-758
    [PMID:28681564]
  13. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  14. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  15. Bustillo-Avendaño E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]