PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG036719t1

Common Name

TCM_036719

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

C2H2

Protein Properties

Length: 509aa MW: 56197.7 Da PI: 6.7856

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG036719t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.5e-07	262	283	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H Thecc1EG036719t1 262 FCTICGKGFKRDANLRMHMRGH 283 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.25E-5	259	286	No hit	No description
PROSITE profile	PS50157	12.03	261	288	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0026	261	283	IPR015880	Zinc finger, C2H2-like
Pfam	PF12874	0.001	262	283	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.5E-6	262	312	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	263	283	IPR007087	Zinc finger, C2H2
SMART	SM00355	53	310	343	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	22	348	370	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 509 aa Download sequence Send to blast
MDLKERLSGE LQKKVPEHPS FTNFNTQHQQ KWEDPSILDY STRIEPPFHV FNQTSQTQSS 60 LPRNPNNQIK VLGQDGPVNE TLLANKVQDW DPSAMLNNLS FLEQKIHQLQ ELVHLIVGRR 120 GQVLGRPDEL VAQQQQLITA DLTSIIVQLI STAGSLLPSV KHTLSAASPS IGQFGQFGGV 180 VFPSGQGLNG GVQPQSAGGS RISEQPNSVD VSSNSGNEQN HIIEEHELKD EEDVEEGENL 240 LPGTYEILQL EKEEILAPHT HFCTICGKGF KRDANLRMHM RGHGDEYKTP AALAKPNKES 300 SSEPTLIKRY SCPYAGCKRN KDHKKFQPLK TILCVKNHYK RTHCDKSYTC SRCNTKKFSV 360 IADLKTHEKH CGKDKWLCSC GTTFSRKDKL FGHITLFQGH TPAIPLDENK GSAGPSDHRG 420 DGNQATNKVG SMNFNFSSNV SSEGGVQSSV DVKGSIDDPA GYFSPLNFDT CNFGGFHEFP 480 RPPFDDSENS FAFLLSGSCN YSQKSGED*

Sequence ? help Back to Top

Protein Sequence Length: 509 aa Download sequence Send to blast

MDLKERLSGE LQKKVPEHPS FTNFNTQHQQ KWEDPSILDY STRIEPPFHV FNQTSQTQSS  60
LPRNPNNQIK VLGQDGPVNE TLLANKVQDW DPSAMLNNLS FLEQKIHQLQ ELVHLIVGRR  120
GQVLGRPDEL VAQQQQLITA DLTSIIVQLI STAGSLLPSV KHTLSAASPS IGQFGQFGGV  180
VFPSGQGLNG GVQPQSAGGS RISEQPNSVD VSSNSGNEQN HIIEEHELKD EEDVEEGENL  240
LPGTYEILQL EKEEILAPHT HFCTICGKGF KRDANLRMHM RGHGDEYKTP AALAKPNKES  300
SSEPTLIKRY SCPYAGCKRN KDHKKFQPLK TILCVKNHYK RTHCDKSYTC SRCNTKKFSV  360
IADLKTHEKH CGKDKWLCSC GTTFSRKDKL FGHITLFQGH TPAIPLDENK GSAGPSDHRG  420
DGNQATNKVG SMNFNFSSNV SSEGGVQSSV DVKGSIDDPA GYFSPLNFDT CNFGGFHEFP  480
RPPFDDSENS FAFLLSGSCN YSQKSGED*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007020278.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A061FKR4	0.0	A0A061FKR4_THECC; C2H2 and C2HC zinc fingers superfamily protein
STRING	EOY17503	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6977	26	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	0.0	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Thecc1EG036719t1
Entrez Gene	18593149

Publications ? help Back to Top
Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]