PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG031118t1

Common Name

TCM_031118

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

bHLH

Protein Properties

Length: 236aa MW: 25981.4 Da PI: 8.1948

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG031118t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36	1.2e-11	77	124	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+ RRdr+N++f eL ++l + + +K +Ka+iL Av+ + +L Thecc1EG031118t1 77 SKACREKLRRDRLNDKFMELGSILEPG---RPPKTDKAAILIDAVRMVTQL 124 5678********************8...89************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.887	73	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.15E-7	76	129	No hit	No description
Gene3D	G3DSA:4.10.280.10	6.3E-13	77	146	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.8E-9	77	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.49E-13	78	148	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.1E-9	79	130	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd14686	0.00264	139	171	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 236 aa Download sequence Send to blast
MVSPENSNYW SHFDYANLID DIPDGPYSSF SWPAQPTNAP SNVVSVENDG SFGDLDGLKE 60 SGSKKRVRSE SCNPSSSKAC REKLRRDRLN DKFMELGSIL EPGRPPKTDK AAILIDAVRM 120 VTQLRGEAQK LKDSNSSLQE KIKELKSEKN ELRDEKQRLK AEKERLEQQL KTMNAQPSFM 180 PPGPAIPAAF AAAQGQAPGN KLVPFIGYPG VAMWQFMPPA AVDTSQDHVL RPPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007021087.2	1e-173	PREDICTED: transcription factor ILR3
Swissprot	Q9FH37	1e-113	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A061F7E8	1e-172	A0A061F7E8_THECC; DNA binding protein, putative
STRING	EOY12612	1e-173	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1437	28	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-102	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thecc1EG031118t1
Entrez Gene	18593688

Publications ? help Back to Top
Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]