PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG018403t1

Common Name

TCM_018403

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

WRKY

Protein Properties

Length: 571aa MW: 61751.2 Da PI: 5.8462

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG018403t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.6	3.5e-30	239	298	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a gCpv+k+v+r+aed +++++tYeg+Hnh+ Thecc1EG018403t1 239 MNDGCQWRKYGQKISKGNPCPRAYYRCTVApGCPVRKQVQRCAEDMSILITTYEGNHNHP 298 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	3.6E-32	224	300	IPR003657	WRKY domain
SuperFamily	SSF118290	3.01E-27	232	300	IPR003657	WRKY domain
PROSITE profile	PS50811	29.264	234	300	IPR003657	WRKY domain
SMART	SM00774	5.0E-37	239	299	IPR003657	WRKY domain
Pfam	PF03106	1.2E-26	240	298	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 571 aa Download sequence Send to blast
MEVLLLKMPR ADAAVKQEKT AQSVVCEEAC SPEARKTDMG RKLPKNSELN SSSPSHEGLV 60 DVKEEDELQS AKSEMGEVKE ENERLKMMLE QIQENYKSLQ LRFFEILQQG AIKKSTDSDP 120 SHDDEAPEPE LVSLSLGRSP TNSKKDEKTG SSGKTKEDQE IKAGLTLGLD SKLQLSTEIV 180 SNPGPENSSE EPKEDDAGET WPPSKIQKTT RNGDEEVAQQ GHVKRARVSV RARCDAPTMN 240 DGCQWRKYGQ KISKGNPCPR AYYRCTVAPG CPVRKQVQRC AEDMSILITT YEGNHNHPLP 300 VSATAMASTT SAAASMLLSG SSTSQPGLIS TATSTLTAEL NGLNFNLHDN SRTRQFYLPN 360 STSPSFPTVT LDLTASPSSS SSYFSRFSTD IPTTARFPSA SLNFSSSESN ILPTVWGNGY 420 PAYGAVPYNQ SHTENLNLGK ESQEQFYQTF LEKNHQTAAS QHSLTETLTK AITSDPSFRS 480 VIAAAISSTV SSSAKSAGQT DQTAERFGQN LMQVISQNLL TQNGKGCATS HFTALTSSSS 540 QTGSSLQSSL PISIFNSAST PASDNKEHNN *

Sequence ? help Back to Top

Protein Sequence Length: 571 aa Download sequence Send to blast

MEVLLLKMPR ADAAVKQEKT AQSVVCEEAC SPEARKTDMG RKLPKNSELN SSSPSHEGLV  60
DVKEEDELQS AKSEMGEVKE ENERLKMMLE QIQENYKSLQ LRFFEILQQG AIKKSTDSDP  120
SHDDEAPEPE LVSLSLGRSP TNSKKDEKTG SSGKTKEDQE IKAGLTLGLD SKLQLSTEIV  180
SNPGPENSSE EPKEDDAGET WPPSKIQKTT RNGDEEVAQQ GHVKRARVSV RARCDAPTMN  240
DGCQWRKYGQ KISKGNPCPR AYYRCTVAPG CPVRKQVQRC AEDMSILITT YEGNHNHPLP  300
VSATAMASTT SAAASMLLSG SSTSQPGLIS TATSTLTAEL NGLNFNLHDN SRTRQFYLPN  360
STSPSFPTVT LDLTASPSSS SSYFSRFSTD IPTTARFPSA SLNFSSSESN ILPTVWGNGY  420
PAYGAVPYNQ SHTENLNLGK ESQEQFYQTF LEKNHQTAAS QHSLTETLTK AITSDPSFRS  480
VIAAAISSTV SSSAKSAGQT DQTAERFGQN LMQVISQNLL TQNGKGCATS HFTALTSSSS  540
QTGSSLQSSL PISIFNSAST PASDNKEHNN *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	1e-21	226	300	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017974754.1	0.0	PREDICTED: probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	1e-122	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A061EM50	0.0	A0A061EM50_THECC; WRKY DNA-binding protein 72, putative
STRING	EOY03394	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2959	28	68

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	4e-99	WRKY DNA-binding protein 72

Link Out ? help Back to Top
Phytozome	Thecc1EG018403t1
Entrez Gene	18601462

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]