PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG006602t1

Common Name

TCM_006602

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

bHLH

Protein Properties

Length: 616aa MW: 69077.3 Da PI: 5.5404

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG006602t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.8	7.1e-12	356	399	7	55
HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 +Er+RR+++N+++ Lr+l+Pk + Kl+ a+iL A+e++k+Lq Thecc1EG006602t1 356 VAERKRRKKLNERLYALRSLVPKiS------KLDRASILGDAIEFVKELQ 399 68*******************66......****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.7E-21	22	167	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	15.663	349	398	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.61E-13	351	403	No hit	No description
SuperFamily	SSF47459	5.5E-17	352	412	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.1E-16	355	404	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.7E-9	356	399	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.2E-16	356	412	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	9.54E-4	496	559	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009555	Biological Process	pollen development
GO:0048657	Biological Process	anther wall tapetum cell differentiation
GO:0005634	Cellular Component	nucleus
GO:0000978	Molecular Function	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 616 aa Download sequence Send to blast
MGVLRMSESL KVKMNIFQNL LERLRQLVGS KGWDYCVLWK LSDDQRFIEW MDCCCAGAEN 60 IESGGELQFP VTPVLPCRDV MFQHPKTKSC ELLAQLPSCM PLDSGSHAQT LISNQPKWLN 120 FSKNSDSNVL EEIVGTRILI PVAGGLVELF VAKQVCEDQN VVDYIATLCN ITLEQGGMMN 180 SSSMDAHVTV LNAQALNELQ PKHHLGNEDD QKDPTNHFQQ PVSLATTLET LNLPYDISSD 240 QIRSCNSPTN SLQQYNYLSE HKTKIDVYVE GSHDAFLPDH KVASPYNDNG LQEMDPLNSI 300 ITNESILIQG NDKDSIKQDN GRSDSMSDCS DQNDDEDDAR YQRRPGSKGP QSKNLVAERK 360 RRKKLNERLY ALRSLVPKIS KLDRASILGD AIEFVKELQN QVKELQDELE EHSDNDGSKK 420 TGLNGIHKNV QSEIFSQNEI AVDPNPEHDK GPNGFPVGGN GSVSKHKQDV EITSDKTQQM 480 EVQVEVAQID GNQFFVKVFC EHKPGGFVRL MEALDSLGLE VTNANVNSFR GLVSNVFKVE 540 IKDSEMVQAD HVRDSLLELT RNPSKGLSEM AKASENNNGI DCNYHKQQQQ LQHQLHNHHI 600 SSHHRHLHHF QKQLA*

Sequence ? help Back to Top

Protein Sequence Length: 616 aa Download sequence Send to blast

MGVLRMSESL KVKMNIFQNL LERLRQLVGS KGWDYCVLWK LSDDQRFIEW MDCCCAGAEN  60
IESGGELQFP VTPVLPCRDV MFQHPKTKSC ELLAQLPSCM PLDSGSHAQT LISNQPKWLN  120
FSKNSDSNVL EEIVGTRILI PVAGGLVELF VAKQVCEDQN VVDYIATLCN ITLEQGGMMN  180
SSSMDAHVTV LNAQALNELQ PKHHLGNEDD QKDPTNHFQQ PVSLATTLET LNLPYDISSD  240
QIRSCNSPTN SLQQYNYLSE HKTKIDVYVE GSHDAFLPDH KVASPYNDNG LQEMDPLNSI  300
ITNESILIQG NDKDSIKQDN GRSDSMSDCS DQNDDEDDAR YQRRPGSKGP QSKNLVAERK  360
RRKKLNERLY ALRSLVPKIS KLDRASILGD AIEFVKELQN QVKELQDELE EHSDNDGSKK  420
TGLNGIHKNV QSEIFSQNEI AVDPNPEHDK GPNGFPVGGN GSVSKHKQDV EITSDKTQQM  480
EVQVEVAQID GNQFFVKVFC EHKPGGFVRL MEALDSLGLE VTNANVNSFR GLVSNVFKVE  540
IKDSEMVQAD HVRDSLLELT RNPSKGLSEM AKASENNNGI DCNYHKQQQQ LQHQLHNHHI  600
SSHHRHLHHF QKQLA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	357	364	ERKRRKKL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269\|PubMed:12535353, ECO:0000269\|PubMed:24804694}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX591220	9e-48	JX591220.1 Gossypium hirsutum clone NBRI_GE26295 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017972012.1	0.0	PREDICTED: transcription factor ABORTED MICROSPORES
Refseq	XP_017972013.1	0.0	PREDICTED: transcription factor ABORTED MICROSPORES
Swissprot	Q9ZVX2	1e-157	AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBL	A0A061DXZ8	0.0	A0A061DXZ8_THECC; Basic helix-loop-helix DNA-binding superfamily protein, putative
STRING	EOX97629	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7589	27	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16910.1	1e-144	bHLH family protein

Link Out ? help Back to Top
Phytozome	Thecc1EG006602t1
Entrez Gene	18607527

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Jiang J,Zhang Z,Cao J Pollen wall development: the associated enzymes and metabolic pathways. Plant Biol (Stuttg), 2013. 15(2): p. 249-63 [PMID:23252839] Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Xu J, et al. ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis. Plant Cell, 2014. 26(4): p. 1544-1556 [PMID:24781116] Qian H, et al. Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis. Ecotoxicology, 2015. 24(1): p. 163-71 [PMID:25348600] Xiong SX, et al. The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana. Plant J., 2016. 88(6): p. 936-946 [PMID:27460657] Ferguson AC, et al. Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis. New Phytol., 2017. 213(2): p. 778-790 [PMID:27787905] Lou Y, et al. Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana. New Phytol., 2018. 217(1): p. 378-391 [PMID:28940573] Bi H,Fan W,Zhang P C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis. Front Plant Sci, 2017. 8: p. 1689 [PMID:29021807]