PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG006252t3
Common NameTCM_006252
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family C2H2
Protein Properties Length: 332aa    MW: 37817.8 Da    PI: 6.0347
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG006252t3genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.50.000443961323
                      ET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                      C+   Cgk+F +   L++H   H
  Thecc1EG006252t3 39 CSyeGCGKTFIDAGALRKHSHIH 61
                      77779**************7766 PP
2zf-C2H217.51.2e-056690123
                      EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                      y+C+   Cgk F ++s LkrH   H
  Thecc1EG006252t3 66 YVCHweGCGKKFLDSSKLKRHFLIH 90
                      9********************8877 PP
3zf-C2H220.99.5e-0796120123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       + Cp   Cgk Fs   nL++H++tH
  Thecc1EG006252t3  96 FICPheGCGKAFSLDFNLRSHMKTH 120
                       78**********************9 PP
4zf-C2H2188.1e-06126150123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       + Cp  dCgk++ + + Lk+Hi +H
  Thecc1EG006252t3 126 HICPypDCGKRYAHEYKLKNHIASH 150
                       679999*****************96 PP
5zf-C2H215.45.2e-05189214123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       y+Cp   C k + + + Lk H+r+ H
  Thecc1EG006252t3 189 YVCPyeGCEKAYIHEYKLKLHLRReH 214
                       99**********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.607.9E-143263IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.7833766IPR007087Zinc finger, C2H2
SMARTSM003550.00323761IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002803961IPR007087Zinc finger, C2H2
SuperFamilySSF576673.44E-84090No hitNo description
Gene3DG3DSA:3.30.160.601.5E-146486IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.00116690IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.9216695IPR007087Zinc finger, C2H2
PROSITE patternPS0002806890IPR007087Zinc finger, C2H2
SuperFamilySSF576674.96E-1381123No hitNo description
Gene3DG3DSA:3.30.160.605.0E-2087120IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.59196125IPR007087Zinc finger, C2H2
SMARTSM003553.9E-496120IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028098120IPR007087Zinc finger, C2H2
SuperFamilySSF576672.48E-8111152No hitNo description
Gene3DG3DSA:3.30.160.602.9E-9121152IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.494126155IPR007087Zinc finger, C2H2
SMARTSM003550.0028126150IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280128151IPR007087Zinc finger, C2H2
SuperFamilySSF576671.03E-5184212No hitNo description
Gene3DG3DSA:3.30.160.607.0E-10184212IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0047189214IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.868189219IPR007087Zinc finger, C2H2
PROSITE patternPS000280191214IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 332 aa     Download sequence    Send to blast
PLLNGSKNEN TLKALKEKEK EPEAPEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI  60
HGERQYVCHW EGCGKKFLDS SKLKRHFLIH TGERDFICPH EGCGKAFSLD FNLRSHMKTH  120
SQENYHICPY PDCGKRYAHE YKLKNHIASH HEKNTTADVP KYATPTEKIT KTPKPSGGAY  180
GSASSDRPYV CPYEGCEKAY IHEYKLKLHL RREHPGHMSD ENVENATPNA DNEMDEASDQ  240
DAYAGKRVNG KSQKQQSRAK PNVKMPPAKI ARQKGSSPVT LPVPKKQWPV KEEVYEEEDS  300
EETEEDRENV EDGWRYADNN EDDDEETEYE D*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-35391508119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007041332.10.0PREDICTED: uncharacterized zinc finger protein At4g06634 isoform X2
SwissprotQ2V3L31e-132YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A061DWZ40.0A0A061DWZ4_THECC; Zinc finger family protein isoform 3 (Fragment)
STRINGEOX971630.0(Theobroma cacao)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.21e-120C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  3. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  4. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]