PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG005131t2
Common NameTCM_005131
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family bHLH
Protein Properties Length: 615aa    MW: 68106.3 Da    PI: 6.756
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG005131t2genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.55.1e-13445491455
                       HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
               HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                       +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Thecc1EG005131t2 445 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 491
                       799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.8E-5652240IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474593.79E-18440504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.047441490IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000837.34E-15444495No hitNo description
Gene3DG3DSA:4.10.280.103.8E-18445504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10445491IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.8E-16447496IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009737Biological Processresponse to abscisic acid
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 615 aa     Download sequence    Send to blast
MKIEVGMGGG AWNDEDKAMV AAVLGTRAFD YLITSSVSNE NLLMTINSDE NLQNKLSDLV  60
DRPNASNFSW NYAIFWQISR SKSSDWVLGW GDGCCREPKE GEESEATRIL NLRLEDETQQ  120
KMRKRVLQKL HTLFGGSDED NYALGLDRVT DTEMFFLASM YFSFPRGEGG PGKCFASGKH  180
VWISDSLKSG SDYCVRSFLT KSAGVQTIVL VPTDVGVVEL GSVRSVPESL ELLQSIRSSF  240
SSNSALLRAK QMAVAIPVVN EKKDENTHFS NLGTLERVEG IPKIFGQDLN NTSHGHSNYR  300
EKLAIRKMED RPTWGACANG GRLSFSSNQN GLHGSGWPHV HGVKQGNPTE FYGSQNTANN  360
FQELVNGARE EFRVNQFQSQ KPVQMQIDFS GATSRPSVIT RPLSAESEHS DVEASCKEEK  420
PSVADERRPR KRGRKPANGR EEPLNHVEAE RQRREKLNQR FYALRAVVPN ISKMDKASLL  480
GDAIAYINEL QAKLKVMEAE REKFGSTSRD SAGLDPNPTV ENHMRAPDID VQAAHNEVVV  540
RVSCPLDSHP ASRVIQAFKE AQVNVVESKL VTADDTVFHT FVIKSQGSEQ LTREKLIAAF  600
SRESSSLQSL SSLG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-29439501264Transcription factor MYC2
5gnj_B2e-29439501264Transcription factor MYC2
5gnj_E2e-29439501264Transcription factor MYC2
5gnj_F2e-29439501264Transcription factor MYC2
5gnj_G2e-29439501264Transcription factor MYC2
5gnj_I2e-29439501264Transcription factor MYC2
5gnj_M2e-29439501264Transcription factor MYC2
5gnj_N2e-29439501264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1426434RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007051528.10.0PREDICTED: transcription factor bHLH13
RefseqXP_017969330.10.0PREDICTED: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A061DSF00.0A0A061DSF0_THECC; Myc2 bHLH protein isoform 1
STRINGEOX956850.0(Theobroma cacao)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  3. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  4. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]