PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG001516t1
Common NameTCM_001516
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family NAC
Protein Properties Length: 510aa    MW: 55264.9 Da    PI: 6.8607
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG001516t1genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM25.92.8e-081812632297
               NAM  22 kvegkk.leleev.ikevdiykv.ePwdLpk.....kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkg 97 
                       kv+gk+ l+l++  ik++d+y   ePw++ +     ++ + ++++yfF+k +kk+++++r n +++ g+W   g+ k+++ ++ 
  Thecc1EG001516t1 181 KVTGKSmLHLDQNlIKDFDLYGEkEPWEIWNlfggcNL-QYSDDLYFFTKLKKKSQNSSRMNGSVSIGMWMGEGSGKPITYSGL 263
                       66777754444445*****996449****754565322.234589**********************************98644 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF527685.4E-8564175No hitNo description
Gene3DG3DSA:3.40.800.204.1E-9470173IPR023801Histone deacetylase domain
PfamPF008508.0E-7674467IPR023801Histone deacetylase domain
CDDcd099922.98E-12674473No hitNo description
SuperFamilySSF1019415.1E-6181262IPR003441NAC domain
Gene3DG3DSA:3.40.800.204.1E-94271507IPR023801Histone deacetylase domain
SuperFamilySSF527685.4E-85274490No hitNo description
PRINTSPR012704.8E-14284307IPR000286Histone deacetylase superfamily
PRINTSPR012704.8E-14318333IPR000286Histone deacetylase superfamily
PRINTSPR012704.8E-14402412IPR000286Histone deacetylase superfamily
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0090042Biological Processtubulin deacetylation
GO:0005634Cellular Componentnucleus
GO:0005829Cellular Componentcytosol
GO:0009507Cellular Componentchloroplast
GO:0003677Molecular FunctionDNA binding
GO:0042903Molecular Functiontubulin deacetylase activity
GO:0043014Molecular Functionalpha-tubulin binding
GO:0043621Molecular Functionprotein self-association
GO:0048487Molecular Functionbeta-tubulin binding
GO:0051721Molecular Functionprotein phosphatase 2A binding
Sequence ? help Back to Top
Protein Sequence    Length: 510 aa     Download sequence    Send to blast
MELQTFRSIS FAGHGRFWKH SISGRKCFSK NIKTLVSCSY STEENDTLPS VKQLCNAKVI  60
YAVAPALGHN KESHPESNAR VPAIVTALAK MELTSKFRGS DILELQNFKL ASADDIASVH  120
AKAYVSGLEK AMDRASEQGL IVIDGSGPTY ATPTTFCESL VAAGAGLALV DSVVMPQPRT  180
KVTGKSMLHL DQNLIKDFDL YGEKEPWEIW NLFGGCNLQY SDDLYFFTKL KKKSQNSSRM  240
NGSVSIGMWM GEGSGKPITY SGLSAVAASK NQLDPPMGFA LIRPPGHHAI PNGPMGFCVF  300
GNVAIAARHA QRIHGLKRVF IIDFDVHHGN GTNDAFLDDP DIFFLSTHQD GSYPGTGRID  360
EIGHGAGEGA TLNLPLPGGS GDTAMRTVFD EVIVPCAQRF KPDIILVSAG YDGHVLDPLA  420
SLQFTTGTYY MLASNIKQLA KELCGGRCVF FLEGGYNLDS LSYSVADSFR AFLGEPSLAP  480
EFDNPAILYE EPSTRVKQAI QRVKHIHSL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1zz0_A4e-47278463133319Histone deacetylase-like amidohydrolase
1zz0_B4e-47278463133319Histone deacetylase-like amidohydrolase
1zz0_C4e-47278463133319Histone deacetylase-like amidohydrolase
1zz0_D4e-47278463133319Histone deacetylase-like amidohydrolase
1zz1_A4e-47278463133319Histone deacetylase-like amidohydrolase
1zz1_B4e-47278463133319Histone deacetylase-like amidohydrolase
1zz1_C4e-47278463133319Histone deacetylase-like amidohydrolase
1zz1_D4e-47278463133319Histone deacetylase-like amidohydrolase
1zz3_A4e-47278463133319Histone deacetylase-like amidohydrolase
1zz3_B4e-47278463133319Histone deacetylase-like amidohydrolase
1zz3_C4e-47278463133319Histone deacetylase-like amidohydrolase
1zz3_D4e-47278463133319Histone deacetylase-like amidohydrolase
2gh6_A4e-47278463133319Histone deacetylase-like amidohydrolase
2gh6_B4e-47278463133319Histone deacetylase-like amidohydrolase
2gh6_C4e-47278463133319Histone deacetylase-like amidohydrolase
2gh6_D4e-47278463133319Histone deacetylase-like amidohydrolase
5g17_A4e-47278463133319HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
5g17_B4e-47278463133319HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
5g3w_C4e-47278463138324HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
5g3w_D4e-47278463138324HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). {ECO:0000250, ECO:0000269|PubMed:16176989}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007048426.21e-180PREDICTED: histone deacetylase 14
SwissprotQ941D61e-150HDA14_ARATH; Histone deacetylase 14
TrEMBLA0A061DJP00.0A0A061DJP0_THECC; Histone deacetylase 14 isoform 1
STRINGEOX925820.0(Theobroma cacao)
Publications ? help Back to Top
  1. Alinsug MV, et al.
    Subcellular localization of class II HDAs in Arabidopsis thaliana: nucleocytoplasmic shuttling of HDA15 is driven by light.
    PLoS ONE, 2012. 7(2): p. e30846
    [PMID:22363501]
  2. Tran HT, et al.
    Arabidopsis thaliana histone deacetylase 14 (HDA14) is an α-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3.
    Plant J., 2012. 71(2): p. 263-72
    [PMID:22404109]
  3. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  4. Hartl M, et al.
    Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis.
    Mol. Syst. Biol., 2017. 13(10): p. 949
    [PMID:29061669]
  5. Lee K,Lee HY,Back K
    Rice histone deacetylase 10 and Arabidopsis histone deacetylase 14 genes encode N-acetylserotonin deacetylase, which catalyzes conversion of N-acetylserotonin into serotonin, a reverse reaction for melatonin biosynthesis in plants.
    J. Pineal Res., 2018.
    [PMID:29247559]